PD-1 抗体 (AA 101-288)
-
- 抗原 See all PD-1 (PDCD1) 抗体
- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
-
抗原表位
- AA 101-288
-
适用
- 人, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This PD-1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for Programmed cell death protein 1(PDCD1) detection. Tested with WB in Human,Rat.
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
-
Rabbit IgG polyclonal antibody for Programmed cell death protein 1(PDCD1) detection. Tested with WB in Human,Rat.
Gene Name: programmed cell death 1
Protein Name: Programmed cell death protein 1 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human PD1 recombinant protein (Position: P101-L288). Human PD1 shares 59% amino acid (aa) sequence identity with mouse PD1.
- 亚型
- IgG
- Top Product
- Discover our top product PDCD1 Primary Antibody
-
-
- 应用备注
-
WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, The detection limit for PD1 is approximately 0.5 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
-
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
-
- 抗原
- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
- 别名
- PDCD1 (PDCD1 产品)
- 别名
- CD279 antibody, PD-1 antibody, PD1 antibody, SLEB2 antibody, hPD-1 antibody, hPD-l antibody, Ly101 antibody, Pdc1 antibody, programmed cell death 1 antibody, PDCD1 antibody, Pdcd1 antibody
- 背景
-
PDCD1(Programmed cell death 1), also called PD1, encodes a cell surface receptor that is a member of the B7 superfamily involved in immunomodulation. This gene is mapped to 2q37.3. PDCD1 acts as an inhibitory molecule on T cells after interacting with its ligands PDL1 and PDL2. The PDCD1 gene contains 5 exons. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. Using flow cytometric analysis, It has been found that expression of PDCD1 was upregulated on CD16-positive and CD16-negative monocytes, but not on dendritic cells, in viremic HIV-positive patients, but not in highly active antiretroviral therapy (HAART)-treated HIV-positive patients. PDCD1 upregulation in monocytes was induced by microbial Toll-like receptor ligands and inflammatory cytokines.
Synonyms: CD279 antibody|CD279 antigen antibody|hPD l antibody|hPD-1 antibody|hSLE1 antibody|PD 1 antibody|PD-1 antibody|PD1 antibody|PDCD 1 antibody|PDCD1 antibody|PDCD1_HUMAN antibody|Programmed cell death 1 antibody|Programmed cell death protein 1 antibody|Protein PD 1 antibody|Protein PD-1 antibody|SLEB2 antibody|Systemic lupus erythematosus susceptibility 2 antibody - 基因ID
- 5133
- UniProt
- Q15116
- 途径
- Cancer Immune Checkpoints
-