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IRF4 抗体 (AA 272-451)

IRF4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042469
发货至: 中国
  • 抗原 See all IRF4 抗体
    IRF4 (Interferon Regulatory Factor 4 (IRF4))
    抗原表位
    • 8
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
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    AA 272-451
    适用
    • 41
    • 19
    • 14
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 31
    • 7
    • 2
    • 1
    • 1
    克隆类型
    • 34
    • 8
    多克隆
    标记
    • 35
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IRF4 antibody is un-conjugated
    应用范围
    • 33
    • 15
    • 10
    • 6
    • 6
    • 6
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Interferon regulatory factor 4(IRF4) detection. Tested with WB, IHC-P in Human.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Interferon regulatory factor 4(IRF4) detection. Tested with WB, IHC-P in Human.
    Gene Name: interferon regulatory factor 4
    Protein Name: Interferon regulatory factor 4
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human MUM1 recombinant protein (Position: E272-E451). Human MUM1 shares 92% amino acid (aa) sequence identity with mouse MUM1.
    亚型
    IgG
    Top Product
    Discover our top product IRF4 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for MUM1 is approximately 0.2 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    IRF4 (Interferon Regulatory Factor 4 (IRF4))
    别名
    IRF4 (IRF4 产品)
    别名
    LSIRF antibody, MUM1 antibody, NF-EM5 antibody, AI385587 antibody, IRF-4 antibody, Spip antibody, IRF4 antibody, si:ch73-170d1.2 antibody, irf4 antibody, interferon regulatory factor 4 antibody, interferon regulatory factor 4a antibody, Interferon regulatory factor 4 antibody, PWWP domain-containing protein MUM1 antibody, IRF4 antibody, Irf4 antibody, irf4a antibody, irf4 antibody, LOC612320 antibody, LOC100068881 antibody
    背景
    Interferon regulatory factor 4 (IRF4), also known as MUM1, is a protein that in humans is encoded by the IRF4 gene. It is located on 6p25.3. IRF4 is a transcription factor, and it is essential for the development of T helper-2 (Th2) cells, IL17 -producing Th17 cells, and IL9 -producing Th9 cells. In melanocytic cells, the IRF4 gene may be regulated by MITF. IRF4 is a transcription factor that has been implicated in acute leukemia. This gene is strongly associated with pigmentation, sensitivity of skin to sun exposure, freckles, blue eyes, and brown hair color. What's more, IRF4 inhibition is toxic to myeloma cell lines, regardless of transforming oncogenic mechanism.

    Synonyms: Interferon regulatory factor 4 antibody|IRF 4 antibody|IRF-4 antibody|Irf4 antibody|IRF4_HUMAN antibody|LSIRF antibody|Lymphocyte specific interferon regulatory factor antibody|Lymphocyte specific IRF antibody|Lymphocyte-specific interferon regulatory factor antibody|Multiple myeloma oncogene 1 antibody|MUM 1 antibody|MUM1 antibody|NF EM5 antibody|NF-EM5 antibody|NFEM5 antibody|PU.1 interaction partner antibody|Sfpi1/PU.1 interaction partner antibody|Transcriptional activator PIP antibody
    基因ID
    3662
    UniProt
    Q15306
    途径
    Chromatin Binding
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