HEXB 抗体 (AA 381-556)
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- 抗原 See all HEXB 抗体
- HEXB (Hexosaminidase B (Beta Polypeptide) (HEXB))
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抗原表位
- AA 381-556
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HEXB antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Beta-hexosaminidase subunit beta(HEXB) detection. Tested with WB, IHC-P in Human.
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Beta-hexosaminidase subunit beta(HEXB) detection. Tested with WB, IHC-P in Human.
Gene Name: hexosaminidase B (beta polypeptide)
Protein Name: Beta-hexosaminidase subunit beta - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human HEXB recombinant protein (Position: K381-M556). Human HEXB shares 75% and 73% amino acid (aa) sequences identity with mouse and rat HEXB, respectively.
- 亚型
- IgG
- Top Product
- Discover our top product HEXB Primary Antibody
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for HEXB is approximately 0.2 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- HEXB (Hexosaminidase B (Beta Polypeptide) (HEXB))
- 别名
- HEXB (HEXB 产品)
- 别名
- ENC-1AS antibody, hexosaminidase B antibody, hexosaminidase subunit beta antibody, Hexb antibody, HEXB antibody
- 背景
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Beta-hexosaminidase subunit beta (HEXB) is an enzyme that in humans is encoded by the HEXB gene. It is mapped to 5q13.3. HEXB is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). It has been found that HEXB is a peptidoglycan hydrolase and it is involved in restricting mycobacteria growth even before the onset of adaptive immunity.
Synonyms: Beta hexosaminidase beta chain antibody|Beta hexosaminidase subunit beta antibody|Beta N acetylhexosaminidase antibody|Beta-hexosaminidase subunit beta chain A antibody|Beta-N-acetylhexosaminidase subunit beta antibody|Cervical cancer proto oncogene 7 protein antibody|Cervical cancer proto-oncogene 7 protein antibody|ENC 1AS antibody|HCC 7 antibody|HCC-7 antibody|HCC7 antibody|HEX B antibody|Hexb antibody|HEXB_HUMAN antibody|Hexosaminidase B (beta polypeptide) antibody|Hexosaminidase B antibody|Hexosaminidase subunit B antibody|HexosaminidaseB antibody|N acetyl beta glucosaminidase antibody|N-acetyl-beta-glucosaminidase subunit beta antibody - 基因ID
- 3074
- UniProt
- P07686
- 途径
- Sensory Perception of Sound, Glycosaminoglycan Metabolic Process
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