GFRA1 抗体 (AA 25-227)
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- 抗原 See all GFRA1 抗体
- GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))
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抗原表位
- AA 25-227
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GFRA1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for GDNF family receptor alpha-1(GFRA1) detection. Tested with WB, IHC-P in Human.
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for GDNF family receptor alpha-1(GFRA1) detection. Tested with WB, IHC-P in Human.
Gene Name: GDNF family receptor alpha 1
Protein Name: GDNF family receptor alpha-1 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human GFRA1 recombinant protein (Position: D25-Q227). Human GFRA1 shares 97% amino acid (aa) sequence identity with both mouse and rat GFRA1.
- 亚型
- IgG
- Top Product
- Discover our top product GFRA1 Primary Antibody
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for GFRA1 is approximately 0.2 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))
- 别名
- GFRA1 (GFRA1 产品)
- 别名
- gdnfr antibody, ret1l antibody, retl1 antibody, trnr1 antibody, gdnfra antibody, MGC122616 antibody, gfr-alpha-1 antibody, GDNFR antibody, GDNFRA antibody, GFR-ALPHA-1 antibody, RET1L antibody, RETL1 antibody, TRNR1 antibody, GDNFRALPHA antibody, GFRA1 antibody, AU042498 antibody, gfralpha1a antibody, zgc:110129 antibody, GDNF family receptor alpha 1 antibody, glial cell line derived neurotrophic factor family receptor alpha 1 antibody, gdnf family receptor alpha 1a antibody, gfra1 antibody, GFRA1 antibody, Gfra1 antibody, gfra1a antibody
- 背景
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GDNF family receptor alpha-1 (GFRα1), also known as the GDNF receptor or GFRA1, is a protein that in humans is encoded by the GFRA1 gene. It is mapped to chromosome 10q25.3. The protein encoded by this gene is a member of the GDNF receptor family. GFRA1 is released by neuronal cells, Schwann cells, and injured sciatic nerve. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is also a candidate gene for Hirschsprung disease. Soluble GFRA1 mediates robust recruitment of RET to lipid rafts via a mechanism requiring the RET tyrosine kinase.
Synonyms: GDNF Family Receptor Alpha 1 antibody|GDNF R antibody|GDNF RA antibody|GDNF receptor alpha antibody|GDNFR alpha 1 antibody|GDNFR alpha antibody|GDNFR antibody|GDNFRA antibody|GDNFRalpha antibody|GFR alpha 1 antibody|GFR alpha1 antibody|GFR-ALPHA-1 antibody|GFRA 1 antibody|GFRA1 antibody|GFRalpha1 antibody|Glial Cell Line DErived Neurotrophic Factor Receptor Alpha antibody|Glial cell line-derived neurotrophic factor receptor alpha antibody|GPI linked anchor protein antibody|GPI-linked anchor protein antibody|MGC23045 antibody|PI linked cell surface accessory protein antibody|RET 1L antibody|RET ligand 1 antibody|RET1L antibody|RETL 1 antibody|RETL1 antibody|TGF beta related neurotrophic factor receptor 1 antibody|TGF-beta related neurotrophic factor receptor 1 antibody|TRNR 1 antibody|TRNR1 antibody - 基因ID
- 14585
- UniProt
- P56159
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