Crossover junction endonuclease EME1 (EME1) (AA 520-561), (C-Term) 抗体
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- 抗原 See all Crossover junction endonuclease EME1 (EME1) 抗体
- Crossover junction endonuclease EME1 (EME1)
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抗原表位
- AA 520-561, C-Term
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Crossover junction endonuclease EME1(EME1) detection. Tested with WB, IHC-P in Human,Rat.
- 序列
- DKERQNLLAD IQVRRGEGVT STSRRIGPEL SRRIYLQMTT LQ
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Crossover junction endonuclease EME1(EME1) detection. Tested with WB, IHC-P in Human,Rat.
Gene Name: essential meiotic structure-specific endonuclease 1
Protein Name: Crossover junction endonuclease EME1 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human EME1 (520-561aa DKERQNLLADIQVRRGEGVTSTSRRIGPELSRRIYLQMTTLQ ), different from the related mouse sequence by five amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product EME1 Primary Antibody
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- Crossover junction endonuclease EME1 (EME1)
- 别名
- EME1 (EME1 产品)
- 别名
- 6820428D13 antibody, essential meiotic structure-specific endonuclease 1 antibody, Eme1 antibody
- 背景
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Crossover junction endonuclease EME1 is an enzyme that in humans is encoded by the EME1 gene. It is mapped to 17q21.33. This gene encodes a protein that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures. Also, this protein may be involved in repairing DNA damage and in maintaining genomic stability. Alternative splicing results in multiple transcript variants.
Synonyms: 6820428D13 antibody|Crossover junction endonuclease EME1 antibody|EC 3.1.22.- antibody|EME1 antibody|Eme1 essential meiotic endonuclease 1 homolog 1 (S. pombe) antibody|EME1, S. pombe, homolog of, 1 antibody|EME1_HUMAN antibody|essential meiotic endonuclease 1 homolog 1 (S pombe) antibody|Essential Meiotic Endonuclease 1 Homolog 1 antibody|essential meiotic endonuclease 1 homolog 2 antibody|Essential meiotic endonuclease 1, S. pombe, homolog of, 1 antibody|FLJ31364 antibody|hMMS4 antibody|homolog of yeast EME1 endonuclease antibody|MGC106543 antibody|MMS4 antibody|MMS4 homolog antibody|MMS4L antibody - 基因ID
- 146956
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