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Myeloperoxidase 抗体 (AA 406-745)

MPO 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042368
发货至: 中国
  • 抗原 See all Myeloperoxidase (MPO) 抗体
    Myeloperoxidase (MPO)
    抗原表位
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    AA 406-745
    适用
    • 176
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    人, 小鼠, 大鼠
    宿主
    • 132
    • 79
    • 1
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    • 1
    克隆类型
    • 125
    • 89
    多克隆
    标记
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    This Myeloperoxidase antibody is un-conjugated
    应用范围
    • 119
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Myeloperoxidase(MPO) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Myeloperoxidase(MPO) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: myeloperoxidase
    Protein Name: Myeloperoxidase
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human Myeloperoxidase recombinant protein (Position:S406-S745). Human Myeloperoxidase shares 90% amino acid (aa) sequence identity with mouse Myeloperoxidase.
    亚型
    IgG
    Top Product
    Discover our top product MPO Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for Myeloperoxidase is approximately 0.25 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Wei, Kong, Li, Guan, Wang, Miao: "Nicotinamide mononucleotide attenuates brain injury after intracerebral hemorrhage by activating Nrf2/HO-1 signaling pathway." in: Scientific reports, Vol. 7, Issue 1, pp. 717, (2018) (PubMed).

    Xu, Zhang, He, Li, Gao, Liu: "Lactobacillus acidophilus alleviates pouchitis after ileal pouch-anal anastomosis in rats." in: World journal of gastroenterology, Vol. 23, Issue 26, pp. 4735-4743, (2018) (PubMed).

    Wang, Liu, Liu, Wang, Fan, Ma, Jin, Xiang, Huang, Zhang, Xu, Yin, He: "Interleukin-17A Aggravates Middle Ear Injury Induced by Streptococcus pneumoniae through the p38 Mitogen-Activated Protein Kinase Signaling Pathway." in: Infection and immunity, Vol. 85, Issue 10, (2017) (PubMed).

    Yu, Chen, Wang, Kuang, Liu, Zhang, Du: "Neuroprotective effect of kaempferol glycosides against brain injury and neuroinflammation by inhibiting the activation of NF-?B and STAT3 in transient focal stroke." in: PLoS ONE, Vol. 8, Issue 2, pp. e55839, (2013) (PubMed).

  • 抗原
    Myeloperoxidase (MPO)
    别名
    MPO (MPO 产品)
    别名
    mKIAA4033 antibody, MPO antibody, LOC100335032 antibody, POX2' antibody, XPOX2' antibody, mpo antibody, mpo-A antibody, pmr-1 antibody, pmr1 antibody, pox2 antibody, xpox2 antibody, myeloperoxidase antibody, myeloperoxidase L homeolog antibody, MPO antibody, Mpo antibody, LOC100335032 antibody, mpo.L antibody
    背景
    Myeloperoxidase (MPO) is a mammalian phagocyte hemoprotein thought to primarily mediate host defense reactions. It is abundantly expressed in neutrophils and secreted during their activation. Myeloperoxidase is part of the host defense system of human polymorphonuclear leukocytes, responsible for microbicidal activity against a wide range of organisms. It is located in the nucleus as well as in the cytoplasm. Intranuclear MPO may help to protect DNA against damage resulting from oxygen radicals produced during myeloid cell maturation and function. The standard product used in this kit is the product of gene recombination, consisting of 697(A49-S745) amino acids with the molecular mass of 80KDa.

    Synonyms: 84 kDa myeloperoxidase antibody|89 kDa myeloperoxidase antibody|EC 1.11.1.7 antibody|EC1.11.2.2 antibody|MPO antibody|Myeloperoxidase heavy chain antibody|Myeloperoxidase light chain antibody|PERM_HUMAN antibody
    基因ID
    4353
    UniProt
    P05164
    途径
    Chromatin Binding
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