SCO2 antibody was raised against Synthetic Peptide (-KLH conjugated) corresponding to 19 Amino Acid peptide from near the carboxy terminus of Human SCO2.
Western Blot. Immunohistochemistry on Paraffin Sections (2.5 μg/mL). This SCO2 antibody was validated for use in immunohistochemistry on a panel of 21formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigenretrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides wereincubated with biotinylated secondary antibody LS-D1, followed by alkalinephosphatase-streptavidin and chromogen. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
CEMCOX1 antibody, MYP6 antibody, SCO1L antibody, SCO cytochrome oxidase deficient homolog 2 (yeast) antibody, SCO2 cytochrome c oxidase assembly protein antibody, SCO2, cytochrome c oxidase assembly protein antibody, SCO2 antibody, Sco2 antibody
背景
Mammalian cytochrome c oxidase (COX) catalyzes the transfer of reducing equivalents from Cytochrome C to molecular oxygen and pumps protons across the inner mitochondrial membrane. In yeast, 2 related COX assembly genes, SCO1 and SCO2 (synthesis of Cytochrome C Oxidase), enable subunits 1 and 2 to be incorporated into the holoprotein. This gene is the human homolog of the yeast SCO2 gene.Synonyms: Protein SCO2 homolog mitochondrial