Prohibitin 2 抗体 (Middle Region)
-
- 抗原 See all Prohibitin 2 (PHB2) 抗体
- Prohibitin 2 (PHB2)
-
抗原表位
- Middle Region
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Prohibitin 2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- 纯化方法
- Antigen affinity
- 免疫原
- An amino acid sequence from the middle region of human REA/PHB2 (RPNAQELPSMYQRLGLDY) was used as the immunogen for this Prohibitin 2 antibody (100% homologous in human, mouse and rat).
- 亚型
- IgG
- Top Product
- Discover our top product PHB2 Primary Antibody
-
anti-Prohibitin 2 (PHB2) antibody
PHB2 适用: 人 WB, IHC, IP, IF 宿主: 兔 Monoclonal unconjugated
anti-Prohibitin 2 (PHB2) antibodyPHB2 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Prohibitin 2 (PHB2) (C-Term) antibodyPHB2 适用: 人, 小鼠, 大鼠, 兔, 豚鼠, Cow, 犬, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Prohibitin 2 (PHB2) (AA 1-299) antibodyPHB2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Prohibitin 2 (PHB2) (AA 197-226), (C-Term) antibodyPHB2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB10631 unconjugated
anti-Prohibitin 2 (PHB2) antibodyPHB2 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Prohibitin 2 (PHB2) (Tyr128) antibodyPHB2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Prohibitin 2 (PHB2) (AA 1-299) antibodyPHB2 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Prohibitin 2 (PHB2) (AA 225-255) antibodyPHB2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB15576 unconjugated
anti-Prohibitin 2 (PHB2) (AA 111-128), (Middle Region) antibodyPHB2 适用: 人, 小鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- The stated application concentrations are suggested starting amounts. Titration of the Prohibitin 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL
- 限制
- 仅限研究用
-
- 缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 储存条件
- -20 °C
- 储存方法
- After reconstitution, the Prohibitin 2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
-
- 抗原
- Prohibitin 2 (PHB2)
- 别名
- Prohibitin 2 (PHB2 产品)
- 别名
- bcap37 antibody, zgc:73150 antibody, wu:fc28c08 antibody, PHB2 antibody, phb2 antibody, ATPHB2 antibody, F21M11.21 antibody, F21M11_21 antibody, prohibitin 2 antibody, DKFZp469N1310 antibody, BAP antibody, BCAP37 antibody, Bap37 antibody, PNAS-141 antibody, REA antibody, p22 antibody, bap37 antibody, prohibitin2 antibody, xphb2 antibody, AU044498 antibody, Bcap37 antibody, Bap antibody, Bap-37 antibody, Bcap27 antibody, prohibitin 2a antibody, prohibitin 2 antibody, prohibitin 2 S homeolog antibody, phb2a antibody, PHB2 antibody, phb2 antibody, phb2.S antibody, Phb2 antibody
- 背景
- Prohibitin 2, also called Repressor of Estrogen Receptor Activity (REA), is a protein that in humans is encoded by the PHB2 gene. The International Radiation Hybrid Mapping Consortium mapped the gene to chromosome 12. Montano et al.(1999) showed that REA enhanced the potency of a dominant-negative ER-alpha mutant and antiestrogens as suppressors of ER-alpha activity in Chinese hamster ovary cells. When coexpressed with wildtype ER-alpha or ER-beta(ESR2), PHB2 suppressed activation of a reporter gene in a dose-dependent manner. It had no effect on reporter activity in the absence of liganded ER, and it had no effect on the transcriptional activities of other hormone receptors. Mutation analysis showed that an N-terminal domain and a central domain of PHB2 were required for its repressor activity.
- UniProt
- Q99623
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
-
