Peroxiredoxin 3 抗体 (AA 110-256)
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- 抗原 See all Peroxiredoxin 3 (PRDX3) 抗体
- Peroxiredoxin 3 (PRDX3)
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抗原表位
- AA 110-256
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Peroxiredoxin 3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Antigen affinity
- 免疫原
- Human partial recombinant protein (AA 110-256) was used as the immunogen for this PRDX3 antibody.
- 亚型
- IgG
- Top Product
- Discover our top product PRDX3 Primary Antibody
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- 应用备注
- The stated application concentrations are suggested starting amounts. Titration of the PRDX3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,ICC: 0.5-1 μg/mL
- 限制
- 仅限研究用
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- 缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 储存条件
- -20 °C
- 储存方法
- After reconstitution, the PRDX3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- 抗原
- Peroxiredoxin 3 (PRDX3)
- 别名
- PRDX3 (Peroxiredoxin 3) (PRDX3 产品)
- 别名
- cb718 antibody, wu:fk49e09 antibody, zgc:110282 antibody, zgc:112512 antibody, MGC83969 antibody, PRDX3 antibody, AOP-1 antibody, AOP1 antibody, HBC189 antibody, MER5 antibody, PRO1748 antibody, SP-22 antibody, prx-III antibody, AW822249 antibody, Aop1 antibody, D0Tohi1 antibody, Ef2l antibody, Mer5 antibody, Prx3 antibody, SP22 antibody, TDXM antibody, MTAP antibody, peroxiredoxin 3 antibody, peroxiredoxin 3 S homeolog antibody, peroxiredoxin PRX3 antibody, prdx3 antibody, PRDX3 antibody, prdx3.S antibody, PRX3 antibody, Prdx3 antibody
- 背景
- Peroxiredoxin 3, also known as AOP-1, MER5, SP-22 or PRX3, is localized exclusively in mitochondria. The deduced 256-amino acid human protein shares 86 % amino acid sequence similarity with mouse, and significant similarity with both the human proliferation-associated gene A product and the mouse stress-induced peritoneal macrophage protein Msp23. The PRDX3 gene is mapped on 10q26.11. Expression of Peroxiredoxin 3 is induced by MYC and is reduced in c-myc -/- cells. Chromatin immunoprecipitation analysis spanning the entire PRDX3 genomic sequence revealed that MYC binds preferentially to a 930-bp region surrounding exon 1. Results using mitochondria-specific fluorescent probes demonstrated that Peroxiredoxin 3 is essential for maintaining mitochondrial mass and membrane potential in transformed rat and human cells. These data provided evidence that PRDX3 is a MYC target gene that is required to maintain normal mitochondrial function.
- 基因ID
- 10935
- 途径
- Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
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