Netrin 1 抗体 (AA 32-51)
Quick Overview for Netrin 1 抗体 (AA 32-51) (ABIN3031963)
抗原
See all Netrin 1 (NTN1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 32-51
-
纯化方法
- Antigen affinity
-
免疫原
- Amino acids 32-51 (AGQAAQPDPCSDENGHPRRC) were used as the immunogen for this Netrin 1 antibody (100% homologous in human, mouse and rat).
-
亚型
- IgG
-
-
anti-Netrin 1 (NTN1) (C-Term) antibody
Verified NTN1 适用: 人 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Netrin 1 (NTN1) (AA 501-604) antibodyNTN1 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Netrin 1 (NTN1) (C-Term) antibodyNTN1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Netrin 1 (NTN1) (AA 181-195), (Secreted) antibodyNTN1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Netrin 1 (NTN1) (C-Term) antibodyNTN1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Netrin 1 (NTN1) (AA 186-478) antibodyNTN1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Netrin 1 (NTN1) (C-Term) antibodyNTN1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Netrin 1 (NTN1) antibodyMicroarray verified NTN1 适用: 人 IHC 宿主: 小鼠 Monoclonal MAB935839 unconjugated
anti-Netrin 1 (NTN1) antibodyMicroarray verified NTN1 适用: 人 IHC 宿主: 小鼠 Monoclonal MAB577874 unconjugated
anti-Netrin 1 (NTN1) (C-Term) antibodyNTN1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- The stated application concentrations are suggested starting amounts. Titration of the Netrin 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
-
限制
- 仅限研究用
-
-
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- -20 °C
-
储存方法
- After reconstitution, the Netrin 1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
-
-
- Netrin 1 (NTN1)
-
别名
- Netrin 1
-
背景
- Netrin-1 (NTN1), also known as NTN1L, is a diffusible protein made by floor plate cells. It is found in the floor plate and neuroepithelial cells of the ventral region of the spinal cord, as well as other locations in the nervous system including the somatic mesoderm, pancreas and cardiac muscle. The human NTN1 gene is mapped to chromosome 17p13-p12 by FISH. Netrin-1 can attract spinal commissural axons and repel trochlear axons in vitro. And expression confers a selective advantage for tumor cell survival. The binding of netrin-1 to DCC appears to depend on the presence of a coreceptor or accessory proteins. Adenosine A2b receptor is actually its receptor and induces cAMP accumulation on binding netrin-1, and that dependent outgrowth of dorsal spinal cord axons directly involves A2b. Netrin-1 can promote intestinal tumor development, probably by regulating cell survival. Thus, a receptor or receptors function as conditional tumor suppressors.
-
UniProt
- O95631
-
途径
- Regulation of Cell Size
抗原
-
