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LRP5 抗体 (C-Term)

LRP5 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3031640
发货至: 中国
  • 抗原 See all LRP5 抗体
    LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))
    抗原表位
    • 15
    • 15
    • 8
    • 7
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 58
    • 45
    • 21
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 62
    • 5
    • 1
    • 1
    克隆类型
    • 65
    • 4
    多克隆
    标记
    • 24
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LRP5 antibody is un-conjugated
    应用范围
    • 31
    • 26
    • 26
    • 13
    • 13
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    Antigen affinity
    免疫原
    An amino acid sequence from the C-terminus of human Low-density lipoprotein receptor-related protein 5 (IHAVEEVSLEEFSAH) was used as the immunogen for this LRP5 antibody (100% homologous in human, mouse and rat).
    亚型
    IgG
    Top Product
    Discover our top product LRP5 Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the LRP5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the LRP5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))
    别名
    LRP5 (LRP5 产品)
    背景
    Low-density lipoprotein receptor-related protein 5 is a protein that in humans is encoded by the LRP5 gene. LRP5 is a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with diabetes mellitus type 1 in humans. This protein plays a key role in skeletal homeostasis. In addition to that, the binding of Axin to LRP5 is an important part of the Wnt signal transduction pathway, and it also acts as a target for the inhibitory effects of Dickkopf, another developmental protein, on Wnt signaling.
    UniProt
    O75197
    途径
    WNT signaling, Stem Cell Maintenance, Positive Regulation of fat Cell Differentiation
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