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Lamin A/C 抗体 (AA 455-469)

LMNA 适用: 人, 小鼠, 大鼠 WB, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

Western blot testing of Lamin A/C antibody and Lane 1: HeLa; 2: A431 cell lysate (Lamin A/C 抗体 (AA 455-469))

IHC-P: Lamin A/C antibody testing of human lung cancer tissue (Lamin A/C 抗体 (AA 455-469))

IHC-P: Lamin A/C antibody testing of mouse intestine tissue (Lamin A/C 抗体 (AA 455-469))

Western blot testing of Lamin A/C antibody and Lane 1: HeLa (Lamin A/C 抗体 (AA 455-469))

IHC-P: Lamin A/C antibody testing of mouse intestine tissue (Lamin A/C 抗体 (AA 455-469))

IHC-P: Lamin A/C antibody testing of rat intestine tissue (Lamin A/C 抗体 (AA 455-469))

6 images

产品编号 ABIN3031585

发货至: 中国

Datasheet as PDF

抗原 See all Lamin A/C (LMNA) 抗体

Lamin A/C (LMNA)
抗原表位
11

8

8

8

7

7

7

6

5

4

4

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 455-469
适用
143

82

79

27

15

13

8

7

6

6

6

4

4

3

3

2

2

1

1

1

1

1

1
人, 小鼠, 大鼠
宿主
109

45

2

1
兔
Compatible Secondaries
克隆类型
111

46
多克隆
标记
114

10

9

8

3

3

2

2

1

1

1

1

1

1
This Lamin A/C antibody is un-conjugated
应用范围
126

59

56

46

31

28

27

20

14

7

3

2

2

1

1
Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

纯化方法

Antigen affinity

免疫原

Amino acids 455-469 (RNKSNEDQSMGNWQI) were used as the immunogen for this Lamin A/C antibody (100% homologous in human, mouse and rat).

亚型

IgG

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anti-Lamin A/C (LMNA) antibody
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anti-Lamin A/C (LMNA) antibody
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anti-Lamin A/C (LMNA) (AA 481-646) antibody
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anti-Lamin A/C (LMNA) antibody
LMNA 适用: 人, 小鼠, 大鼠, Cow, 犬 WB, IHC, ICC, FACS, IHC (fro) 宿主: 小鼠 Monoclonal 133A2 unconjugated

anti-Lamin A/C (LMNA) (C-Term) antibody
LMNA 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 猴, 马, 兔, Hamster, 小鸡, 绵羊, 豚鼠, 山羊, Avian, Cat, 驴 WB 宿主: 山羊 Polyclonal unconjugated

anti-Lamin A/C (LMNA) (AA 1-664) antibody
LMNA 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

应用备注

The stated application concentrations are suggested starting points. Titration of the Lamin A/C antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL

限制

仅限研究用
缓冲液

0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

储存条件

-20 °C

储存方法

After reconstitution, the Lamin A/C antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
抗原

Lamin A/C (LMNA)

别名

Lamin A/C (LMNA 产品)

别名

CDCD1 antibody, CDDC antibody, CMD1A antibody, CMT2B1 antibody, EMD2 antibody, FPL antibody, FPLD antibody, FPLD2 antibody, HGPS antibody, IDC antibody, LDP1 antibody, LFP antibody, LGMD1B antibody, LMN1 antibody, LMNC antibody, LMNL1 antibody, PRO1 antibody, Dhe antibody, 2459 antibody, 74/76 antibody, CG6944 antibody, D5 antibody, DM[[O]] antibody, Dm antibody, Dm(0) antibody, Dm0 antibody, Dm1 antibody, Dm2 antibody, DmLamin antibody, DmO antibody, Dm[[0]] antibody, Dm[[1]] antibody, Dm[[2]] antibody, Dm[[mit]] antibody, Dm[[o]] antibody, Dmel\\CG6944 antibody, Dmo antibody, LAM antibody, Lam Dm[[0]] antibody, Lam(Dm0) antibody, LamDm[[0]] antibody, LamDm[[o]] antibody, Lam[[Dm0]] antibody, Lamin Dm[[0]] antibody, jf27 antibody, l(2)04643 antibody, l(2)25Ec antibody, l(2)gdh-7 antibody, l(2)gdh7 antibody, l(2)jf27 antibody, lam antibody, lamDm0 antibody, lamDm[[0]] antibody, lamin antibody, lamin Dm0 antibody, lamin Dm[[0]] antibody, misg antibody, nlam antibody, cb948 antibody, fk66d12 antibody, wu:fk66d12 antibody, lmna-A antibody, fpl antibody, idc antibody, lfp antibody, cddc antibody, emd2 antibody, fpld antibody, hgps antibody, ldp1 antibody, lmn1 antibody, lmnc antibody, pro1 antibody, cdcd1 antibody, cmd1a antibody, cmt2b1 antibody, lgmd1b antibody, Lamin-A antibody, lamin-L(III)-like antibody, lamin A/C antibody, lamin A antibody, Lamin antibody, lamin A/C L homeolog antibody, lamin-L(III)-like antibody, LMNA antibody, Lmna antibody, Lam antibody, lmna antibody, lmna.L antibody, LMINA antibody

背景

Lamins are structural protein components of the nuclear lamina, a protein network underlying the inner nuclear membrane that determines nuclear shape and size. There are three types of lamins, A, B and C. The Lamin A/C (LMNA) gene contains 12 exons. Alternative splicing within exon 10 gives rise to two different mRNAs that code for pre-lamin A and C. Lamin A/C mapped to 1q21.2-q21.3 and mutations in this gene cause a variety of human diseases including Emery-Dreifuss muscular dystrophy, dilated cardiomyopathy, and Hutchinson-Gilford progeria syndrome. Protein deficiency is thus associated with both defective nuclear mechanics and impaired mechanically activated gene transcription.

UniProt

P02545

途径

Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus

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