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Integrin alpha 1 抗体 (C-Term)

ITGA1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3031361
发货至: 中国
  • 抗原 See all Integrin alpha 1 (ITGA1) 抗体
    Integrin alpha 1 (ITGA1)
    抗原表位
    • 16
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 64
    • 32
    • 16
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 53
    • 13
    • 1
    • 1
    克隆类型
    • 58
    • 10
    多克隆
    标记
    • 32
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Integrin alpha 1 antibody is un-conjugated
    应用范围
    • 47
    • 23
    • 20
    • 14
    • 13
    • 13
    • 11
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Antigen affinity
    免疫原
    An amino acid sequence from the C-terminus of human Integrin alpha 1 (SNQKRELAIQISKD) was used as the immunogen for this Integrin alpha 1 antibody.
    亚型
    IgG
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the Integrin alpha 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the Integrin alpha 1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Bayer, Svensson, Schjerling, Williams, Wasserman, Kjaer: "Influence of the integrin alpha-1 subunit and its relationship with high-fat diet upon extracellular matrix synthesis in skeletal muscle and tendon." in: Cell and tissue research, Vol. 381, Issue 1, pp. 177-187, (2020) (PubMed).

  • 抗原
    Integrin alpha 1 (ITGA1)
    别名
    Integrin alpha 1 (ITGA1 产品)
    别名
    CD49A antibody, E130012M19Rik antibody, Vla1 antibody, CD49a antibody, VLA1 antibody, integrin alpha 1 antibody, integrin subunit alpha 1 antibody, Itga1 antibody, ITGA1 antibody
    背景
    Integrin alpha 1(ITGA1) chain associates with the beta 1(ITGB1) chain to form a heterodimer that functions as a dual laminin/collagen receptor in neural cells and hematopoietic cells. ITGA1 has a 206-amino acid I domain in its N-terminal half, followed by 3 divalent cation-binding sites and a C-terminal transmembrane domain with a short cytoplasmic tail. It also has 28 potential N-glycosylation sites. Human ITGA1 was expressed in a mouse fibroblast cell line as a 180-kD protein. ITGA1 is involved in the early remodeling of osteoarthritic cartilage and plays an essential role in the regulation of mesenchymal stem cell proliferation and cartilage production. It also plays an essential role in the regulation of MSC proliferation and cartilage production.
    UniProt
    P56199
    途径
    EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex
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