Glutaredoxin 2 抗体 (Middle Region)
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- 抗原 See all Glutaredoxin 2 (GRX2) 抗体
- Glutaredoxin 2 (GRX2)
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抗原表位
- Middle Region
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Glutaredoxin 2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Antigen affinity
- 免疫原
- An amino acid sequence from the middle region of human GLRX2 (EYGNQFQDALYKMTGER) was used as the immunogen for this Glutaredoxin 2 antibody.
- 亚型
- IgG
- Top Product
- Discover our top product GRX2 Primary Antibody
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- 应用备注
- The stated application concentrations are suggested starting amounts. Titration of the Glutaredoxin 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
- 限制
- 仅限研究用
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- 缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 储存条件
- -20 °C
- 储存方法
- After reconstitution, the Glutaredoxin 2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- 抗原
- Glutaredoxin 2 (GRX2)
- 别名
- Glutaredoxin 2 (GRX2 产品)
- 别名
- ECK1049 antibody, JW1051 antibody, CGI-133 antibody, GRX2 antibody, 1700010P22Rik antibody, AI645710 antibody, Grx2 antibody, glutaredoxin 2 (Grx2) antibody, glutaredoxin Grx2 antibody, thioredoxin antibody, glutaredoxin 2 antibody, glutaredoxin 2 (thioltransferase) antibody, grxB antibody, grx2 antibody, AF_RS10790 antibody, GLRX2 antibody, Glrx2 antibody
- 背景
- Glutaredoxin-2 also known as GLRX2 and GRX2, is a protein that in humans is encoded by the GLRX2 gene. Glutaredoxins are a family of glutathione-dependent hydrogen donors that participate in a variety of cellular redox reactions. By sequence analysis, Lundberg et al.(2001) and Gladyshev et al.(2001) identified the GLRX2 gene within a clone mapping to chromosome 1q31.2-q31.3. Lundberg et al.(2001) determined that the gene contains 5 exons spanning about 9.6 kb. The GLRX2B transcript uses a first exon(exon 1B) located upstream from the first exon used by the GLRX2A transcript(exon 1A), suggesting that alternative splicing generates the isoforms. Lundberg et al.(2001)assayed reductase activity in recombinant proteins of both GLRX2 isoforms. They found that both have GSH-dependent dehydroascorbate reductase activity and 2-hydroxyethyl disulfide reductase activity.
- UniProt
- Q9NS18
- 途径
- Cell RedoxHomeostasis
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