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CCR3 抗体 (N-Term)

CCR3 适用: 人 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3030492
发货至: 中国
  • 抗原 See all CCR3 抗体
    CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
    抗原表位
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    N-Term
    适用
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    宿主
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    克隆类型
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    多克隆
    标记
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    This CCR3 antibody is un-conjugated
    应用范围
    • 48
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    纯化方法
    Antigen affinity
    免疫原
    An amino acid sequence from the N-terminus of human C-C chemokine receptor type 3 (MTTSLDTVETFGTTSYYDDV) was used as the immunogen for this CCR3 antibody.
    亚型
    IgG
    Top Product
    Discover our top product CCR3 Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the CCR3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the CCR3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
    别名
    CCR3 (CCR3 产品)
    别名
    CC-CKR-3 antibody, CD193 antibody, CKR3 antibody, CMKBR3 antibody, CC-CKR3 antibody, Cmkbr1l2 antibody, Cmkbr3 antibody, C-C motif chemokine receptor 3 antibody, chemokine (C-C motif) receptor 3 antibody, CCR3 antibody, Ccr3 antibody
    背景
    C-C chemokine receptor type 3, also called CKR3, is a protein that in humans is encoded by the CCR3 gene. The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. This receptor binds and responds to a variety of chemokines, including< a href=../search_result.php?search_txt=eotaxin>eotaxin(CCL11),< a href=../search_result.php?search_txt=eotaxin>eotaxin-3(CCL26),< a href=../search_result.php?search_txt=mcp>MCP-3(CCL7),< a href=../search_result.php?search_txt=mcp>MCP-4(CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. Alternatively spliced transcript variants have been described.
    UniProt
    P51677
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