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BAG3 抗体 (C-Term)

BAG3 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3030138
发货至: 中国
  • 抗原 See all BAG3 抗体
    BAG3 (BCL2-Associated Athanogene 3 (BAG3))
    抗原表位
    • 15
    • 7
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    C-Term
    适用
    • 57
    • 23
    • 17
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
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    • 1
    人, 小鼠, 大鼠
    宿主
    • 58
    • 3
    • 1
    克隆类型
    • 51
    • 11
    多克隆
    标记
    • 27
    • 5
    • 4
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    • 1
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    This BAG3 antibody is un-conjugated
    应用范围
    • 38
    • 22
    • 13
    • 13
    • 12
    • 8
    • 6
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Antigen affinity
    免疫原
    An amino acid sequence from the C-terminus of human BAG family molecular chaperone regulator 3 (LEKLEQKAIDVPGQVQ) was used as the immunogen for this Bag3 antibody (100% homologous in human, mouse and rat).
    亚型
    IgG
    Top Product
    Discover our top product BAG3 Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the BAG3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the BAG3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    BAG3 (BCL2-Associated Athanogene 3 (BAG3))
    别名
    BAG3 (BAG3 产品)
    别名
    bag3-A antibody, MGC53113 antibody, zgc:100859 antibody, BAG3 antibody, ATBAG3 antibody, BCL-2-associated athanogene 3 antibody, T28J14.160 antibody, T28J14_160 antibody, BAG-3 antibody, BIS antibody, CAIR-1 antibody, MFM6 antibody, AA407278 antibody, Bis antibody, mg638 antibody, BCL2 associated athanogene 3 L homeolog antibody, BCL2-associated athanogene 3 antibody, BCL2 associated athanogene 3 antibody, BCL-2-associated athanogene 3 antibody, Bcl2-associated athanogene 3 antibody, bag3.L antibody, bag3 antibody, BAG3 antibody, Bag3 antibody
    背景
    BAG family molecular chaperone regulator 3 is a member of a conserved family of cyto-protective proteins that bind to and regulate Hsp70 family molecular chaperones. BAG3 mutations are responsible for familial dilated cardiomyopathy. Polymorphisms are also associated with sporadic forms of the disease together with HSPB7 locus. In muscle cells, BAG3 cooperates with the molecular chaperones Hsc70 and HspB8 to induce the degradation of mechanically damaged cytoskeleton components in lysosomes. This process is called chaperone-assisted selective autophagy (CASA) and is essential for maintaining muscle activity in flies, mice and men.
    UniProt
    O95817
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