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MORG1 抗体 (N-Term)

wdr83 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3029616
发货至: 中国
  • 抗原 See all MORG1 (wdr83) 抗体
    MORG1 (wdr83) (WD Repeat Domain 83 (wdr83))
    抗原表位
    • 15
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term
    适用
    • 39
    • 33
    • 32
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 49
    • 5
    克隆类型
    • 52
    • 2
    多克隆
    标记
    • 22
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MORG1 antibody is un-conjugated
    应用范围
    • 39
    • 20
    • 13
    • 13
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Antigen affinity
    免疫原
    An amino acid sequence from the N-terminus of human Morg1 (RAVRFNVDGNYCLTC) was used as the immunogen for this Morg1 antibody.
    亚型
    IgG
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  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the Morg1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the Morg1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    MORG1 (wdr83) (WD Repeat Domain 83 (wdr83))
    别名
    Morg1 (wdr83 产品)
    别名
    MORG1 antibody, 1500041N16Rik antibody, Morg1 antibody, RGD1306947 antibody, morg1 antibody, MAPK organizer 1 antibody, wu:fj29g04 antibody, zgc:92654 antibody, WD repeat domain 83 antibody, WD repeat domain containing 83 antibody, WD repeat domain 83 L homeolog antibody, WDR83 antibody, Wdr83 antibody, wdr83.L antibody, wdr83 antibody
    背景
    MORG1(mitogen-activated protein kinase organizer 1), a member of the WD-40 protein family that was isolated as a binding partner of the extracellular signal-regulated kinase(ERK) pathway scaffold protein MP1. MORG1 specifically associates with several components of the ERK pathway, including MP1, Raf-1, MEK, and ERK, and stabilizes their assembly into an oligomeric complex. MORG1 facilitates ERK activation when cells are stimulated with lysophosphatidic acid, phorbol 12-myristate 13-acetate, or serum, but not in response to epidermal growth factor. Suppression of MORG1 by short interfering RNA leads to a marked reduction in ERK activity when cells are stimulated with serum. MORG1 is a component of a modular scaffold system that participates in the regulation of agonist-specific ERK signaling.
    UniProt
    Q9BRX9
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