TSACC/C1orf182 抗体 (Middle Region)
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- 抗原 See all TSACC/C1orf182 (TSACC) products
- TSACC/C1orf182 (TSACC) (TSSK6 Activating Co-Chaperone (TSACC))
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抗原表位
- Middle Region
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TSACC/C1orf182 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- 纯化方法
- Antigen affinity
- 免疫原
- An amino acid sequence from the middle region of human SIAH Interacting Protein (NTRWDYLTQVEKECKE) was used as the immunogen for this SIP antibody (100% homologous in human, mouse and rat).
- 亚型
- IgG
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- 应用备注
- The stated application concentrations are suggested starting amounts. Titration of the SIP antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL
- 限制
- 仅限研究用
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- 缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 储存条件
- -20 °C
- 储存方法
- After reconstitution, the SIP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- 抗原
- TSACC/C1orf182 (TSACC) (TSSK6 Activating Co-Chaperone (TSACC))
- 别名
- SIP (TSACC 产品)
- 别名
- SIP antibody, TP53DINP1 antibody, TP53INP1A antibody, TP53INP1B antibody, Teap antibody, p53DINP1 antibody, C1orf182 antibody, RP11-443G18.5 antibody, SSTK-IP antibody, 1700021C14Rik antibody, C3H1orf182 antibody, RGD1304953 antibody, tumor protein p53 inducible nuclear protein 1 antibody, TSSK6 activating cochaperone antibody, TSSK6 activating co-chaperone antibody, TP53INP1 antibody, TSACC antibody, Tsacc antibody
- 背景
- CACYBP (Calcyclin-binding protein), also called SIP (SIAH Interacting Protein), is a protein that in humans is encoded by the CACYBP gene. The full-length SIP cDNA encodes a predicted 228-amino acid protein. Sequence analysis of the shortest cDNA derived by 2-hybrid screening revealed an 8-amino acid difference in the deduced open reading frame followed by a stop codon, resulting in a predicted 80-amino acid protein, SIP-short (SIPS). The CACYBP gene is mapped on 1q25.1. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. The C-terminal region of SIP that is homologous to SGT1 was able to complement defects in yeast strains containing SGT1 mutant alleles, demonstrating conservation of SGT1 and SIP protein function.
- UniProt
- Q9HB71
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