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Ku70 + Ku80 抗体

KU80 适用: 人, 灵长类 FACS, IF, ICC 宿主: 小鼠 Monoclonal KU729 unconjugated
产品编号 ABIN3026515
发货至: 中国
  • 抗原 See all Ku70 + Ku80 (KU80) products
    Ku70 + Ku80 (KU80) (CG18801 Gene Product From Transcript CG18801-RA (KU80))
    适用
    人, 灵长类
    宿主
    • 2
    • 1
    小鼠
    克隆类型
    • 2
    • 1
    单克隆
    标记
    • 2
    • 1
    This Ku70 + Ku80 antibody is un-conjugated
    应用范围
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)
    无交叉反应
    小鼠, 大鼠, 小鸡
    产品特性
    This antibody recognizes a dimer of two proteins of 70 kDa (Ku70) and ~80 kDa (Ku80), identified as two subunits of Ku. Antbody KU729 recognizes a conformational epitope of the Ku70 + Ku80 dimer, which is destroyed during Western blotting. The Ku70 + Ku80 dimer is important for function of a 460 kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
    纯化方法
    Protein G purified monoclonal antibody
    免疫原
    Nuclear extract of human HL-60 cells was used as the immunogen for this Ku70 + Ku80 antibody.
    克隆位点
    KU729
    亚型
    IgG1 kappa
  • 应用备注
    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Ku70 + Ku80 antibody to be titered up or down for optimal performance.\. Flow cytometry: 0.5-1 μg/10e6 cells,IF: 0.5-1.0 μg/mL,Immunocytochemistry (Acetone-fixed cells): 0.25-0.5 μg/mL for 30 minutes at RT
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    1 mg/mL in 1X PBS, BSA free, sodium azide free
    储存液
    Azide free
    储存条件
    4 °C,-20 °C
    储存方法
    Store the Ku70 + Ku80 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原
    Ku70 + Ku80 (KU80) (CG18801 Gene Product From Transcript CG18801-RA (KU80))
    别名
    Ku70 + Ku80 (KU80 产品)
    背景
    This antibody recognizes a dimer of two proteins of 70  kDa (Ku70) and ~80  kDa (Ku80), identified as two subunits of Ku. Antbody KU729 recognizes a conformational epitope of the Ku70 + Ku80 dimer, which is destroyed during Western blotting. The Ku70 + Ku80 dimer is important for function of a 460  kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
    基因ID
    2547
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