Ku70 + Ku80 抗体 (PE)
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- 抗原 See all Ku70 + Ku80 (KU80) products
- Ku70 + Ku80 (KU80) (CG18801 Gene Product From Transcript CG18801-RA (KU80))
- 适用
- 人, 灵长类
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Ku70 + Ku80 antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF)
- 无交叉反应
- 小鼠, 大鼠, 小鸡
- 产品特性
- This antibody recognizes a dimer of two proteins of 70 kDa (Ku70) and ~80 kDa (Ku80), identified as two subunits of Ku. Antbody KU729 recognizes a conformational epitope of the Ku70 + Ku80 dimer, which is destroyed during Western blotting. The Ku70 + Ku80 dimer is important for function of a 460 kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
- 纯度
- Protein G affinity chromatography
- 免疫原
- Nuclear extract of human HL-60 cells was used as the immunogen for this Ku70 + Ku80 antibody.
- 克隆位点
- KU729
- 亚型
- IgG1 kappa
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- 应用备注
- The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Ku70 + Ku80 antibody to be titered up or down for optimal performance.\. Flow Cytometry : 5 μL/test/million cells or 5 μL/test/100 μL of whole blood,Immunofluorescence : 1:50-1:100 for 30 minutes at RT
- 限制
- 仅限研究用
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- 浓度
- 0.1 mg/mL
- 缓冲液
- 500 μL at 0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store the Ku70 + Ku80 antibody at 2-8°C. Conjugate is light sensitive, store in the dark.
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- 抗原
- Ku70 + Ku80 (KU80) (CG18801 Gene Product From Transcript CG18801-RA (KU80))
- 别名
- Ku70 + Ku80 (KU80 产品)
- 基因ID
- 2547
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