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Ku70 + Ku80 抗体 (PE)

KU80 适用: 人, 灵长类 FACS, IF 宿主: 小鼠 Monoclonal KU729 PE
产品编号 ABIN3026514
发货至: 中国
  • 抗原 See all Ku70 + Ku80 (KU80) products
    Ku70 + Ku80 (KU80) (CG18801 Gene Product From Transcript CG18801-RA (KU80))
    适用
    人, 灵长类
    宿主
    • 2
    • 1
    小鼠
    克隆类型
    • 2
    • 1
    单克隆
    标记
    • 3
    This Ku70 + Ku80 antibody is conjugated to PE
    应用范围
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF)
    无交叉反应
    小鼠, 大鼠, 小鸡
    产品特性
    This antibody recognizes a dimer of two proteins of 70 kDa (Ku70) and ~80 kDa (Ku80), identified as two subunits of Ku. Antbody KU729 recognizes a conformational epitope of the Ku70 + Ku80 dimer, which is destroyed during Western blotting. The Ku70 + Ku80 dimer is important for function of a 460 kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
    纯度
    Protein G affinity chromatography
    免疫原
    Nuclear extract of human HL-60 cells was used as the immunogen for this Ku70 + Ku80 antibody.
    克隆位点
    KU729
    亚型
    IgG1 kappa
  • 应用备注
    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Ku70 + Ku80 antibody to be titered up or down for optimal performance.\. Flow Cytometry : 5 μL/test/million cells or 5 μL/test/100 μL of whole blood,Immunofluorescence : 1:50-1:100 for 30 minutes at RT
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    500 μL at 0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the Ku70 + Ku80 antibody at 2-8°C. Conjugate is light sensitive, store in the dark.
  • 抗原
    Ku70 + Ku80 (KU80) (CG18801 Gene Product From Transcript CG18801-RA (KU80))
    别名
    Ku70 + Ku80 (KU80 产品)
    基因ID
    2547
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