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TAB3 抗体 (N-Term)
TAB3
适用: 人, 小鼠
WB
宿主: 兔
Polyclonal
unconjugated
TAB3抗体详情
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抗原
See all TAB3 抗体
TAB3
(TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3))
抗原表位
All epitopes for TAB3 抗体
N-Term
适用
All reactivities for TAB3 抗体
人, 小鼠
宿主
All hosts for TAB3 抗体
兔
克隆类型
All clonalities for TAB3 抗体
多克隆
标记
All conjugates for TAB3 抗体
This TAB3 antibody is un-conjugated
应用范围
All applications for TAB3 抗体
Western Blotting (WB)
纯化方法
Protein A purified antibody
免疫原
A recombinant protein fragment from the N-terminal region of human TAB3 was used as the immunogen for this antibody.
亚型
IgG
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Discover our top product TAB3 Primary Antibody
Alternatives
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使用细节
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应用备注
Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.\. Western blot: 4-8 μg/mL
限制
仅限研究用
贮存及处理
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浓度
0.5 mg/mL
缓冲液
0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Aliquot the TAB3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
TAB3目标详情
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抗原
TAB3
(TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3))
别名
TAB3 (TAB3 产品 )
别名
MAP3K7IP3 antibody, NAP1 antibody, 4921526G09Rik antibody, Map3k7ip3 antibody, mKIAA4135 antibody, map3k7ip3 antibody, nap1 antibody, tab3 antibody, tab3-a antibody, tab3-b antibody, map3k7ip3l antibody, si:ch211-232d19.8 antibody, si:dkey-30h22.6 antibody, TGF-beta activated kinase 1 and MAP3K7 binding protein 3 antibody, TGF-beta activated kinase 1/MAP3K7 binding protein 3 antibody, TGF-beta activated kinase 1/MAP3K7 binding protein 3 S homeolog antibody, TAB3 antibody, Tab3 antibody, tab3.S antibody, tab3 antibody
背景
TAB3, a TAB2-like protein, is a mediator of TAK1 activation in IL-1 and TNF signaling. IL-1 and TNF are cytokines involved in the inflammation process, initiating signaling cascades leading to the activation of NF-kB and mitogen-activated protein kinases (MAPKs). TAB3 functions as an adapter, linking TAK1 and TRAF6 or TRAF2. This kinase complex phosphorylates IkB, which keeps NF-kB inactive and sequestered in the cytoplasm. Phosphorylation leads to IkB degradation, activating NF-kB, which translocates to the nucleus, binds to DNA response elements and can begin multiple signaling cascades.
基因ID
257397
途径
TLR signaling , Fc-epsilon Receptor Signaling Pathway , Activation of Innate immune Response , Toll-Like Receptors Cascades
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