电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

CLIP 抗体

CLIP 适用: 人 FACS, IF, WB 宿主: 小鼠 Monoclonal CLIP-1133 unconjugated
产品编号 ABIN3026079
发货至: 中国
  • 抗原 See all CLIP products
    CLIP (Corticotropin-Like Intermediate Peptide (CLIP))
    适用
    • 9
    • 4
    • 2
    宿主
    • 6
    • 5
    小鼠
    克隆类型
    • 8
    • 3
    单克隆
    标记
    • 9
    • 1
    • 1
    This CLIP antibody is un-conjugated
    应用范围
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB)
    纯化方法
    Protein G affinity chromatography
    免疫原
    Recombinant full-length human protein was used as the immunogen for the CLIP antibody.
    克隆位点
    CLIP-1133
    亚型
    IgG1 kappa
  • 应用备注
    Optimal dilution of the CLIP antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 1-2 μg/mL,Western blot: 0.5-1 μg/mL
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    1 mg/mL in 1X PBS, BSA free, sodium azide free
    储存液
    Azide free
    储存条件
    4 °C,-20 °C
    储存方法
    Store the CLIP antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原
    CLIP (Corticotropin-Like Intermediate Peptide (CLIP))
    别名
    CLIP (CLIP 产品)
    背景
    Recognizes proteins of 33, 35 and 41  kDa, which are identified as various isoforms of CD74/CLIP. Its epitope is localized in the extracellular domain of CD74. CD74/CLIP is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. The molecule plays a critical role in the presentation of peptides, by the MHC class II antigens, to CD4 positive lymphocytes. CD74/CLIP is expressed on MHC class II positive cells including B cells, a subset of activated T cells, monocytes, and dendritic cells and by various types of carcinomas. It is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74/CLIP stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas and has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma (+).
You are here:
客服