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ZAP70 抗体 (pTyr319)

ZAP70 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3023646
发货至: 中国
  • 抗原 See all ZAP70 抗体
    ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))
    抗原表位
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    pTyr319
    适用
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    宿主
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    克隆类型
    • 179
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    多克隆
    标记
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    This ZAP70 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    序列
    SPYSD
    交叉反应
    产品特性
    Phosphorylated Antibodies
    免疫原
    A synthetic phosphorylated peptide around Y319 of human ZAP70 (NP_001070.2).
    亚型
    IgG
    Top Product
    Discover our top product ZAP70 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:100
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))
    别名
    ZAP70 (ZAP70 产品)
    背景
    This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.,ZAP70,ADMIO2,IMD48,SRK,STCD,STD,TZK,ZAP-70,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Hippo Signaling Pathway,Immunology & Inflammation,T Cell Receptor Signaling Pathway,Protein phosphorylation,ZAP70
    分子量
    35 kDa/55 kDa/69 kDa
    基因ID
    7535
    UniProt
    P43403
    途径
    TCR Signaling, Ubiquitin Proteasome Pathway
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