zgc:101624 antibody, 4921517J08Rik antibody, 4930548B21Rik antibody, GS4 antibody, MLZ-465 antibody, Spdy1 antibody, RINGO antibody, SPDY1 antibody, RINGO3 antibody, RINGOA antibody, SPY1 antibody, Gs4 antibody, Lm23 antibody, Spy1 antibody, speedy homolog A (Xenopus laevis) antibody, speedy/RINGO cell cycle regulator family member A antibody, speedy/RINGO cell cycle regulator family, member A antibody, SPDYA antibody, spdya antibody, Spdya antibody
背景
Regulates the G1/S phase transition of the cell cycle by binding and activating CDK1 and CDK2. Contributes to CDK2 activation without promoting CDK2 phosphorylation, by inducing a conformation change of the CDK2 T-loop that obstructs the substrate-binding cleft prior to kinase activation. Mediates cell survival during the DNA damage process through activation of CDK2.,SPDYA,RINGO3,RINGOA,SPDY1,SPY1,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Kinase,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,SPDYA