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Insulin 抗体 (AA 1-110)

Name: Insulin 抗体 (AA 1-110)
Brand: antibodies-online
SKU: ABIN3022885
Availability: OutOfStock

INS 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated

Western Blotting (WB) image for anti-Insulin (INS) (AA 1-110) antibody (ABIN3022885) (Insulin 抗体 (AA 1-110))

Immunohistochemistry of paraffin-embedded rat pancreatic islet using Insulin Rabbit pAb (ABIN3022884, ABIN3022885, ABIN3022886 and ABIN6219279) at dilution of 1:100 (40x lens). (Insulin 抗体 (AA 1-110))

IHC

Western blot analysis of extracts of Rat pancreas, using Insulin antibody (ABIN3022884, ABIN3022885, ABIN3022886 and ABIN6219279) at 1:1000 dilution. (Insulin 抗体 (AA 1-110))

Immunofluorescence analysis of Rat pancreas using Insulin Rabbit pAb (ABIN3022884, ABIN3022885, ABIN3022886 and ABIN6219279) at dilution of 1:100. (Insulin 抗体 (AA 1-110))

Immunofluorescence analysis of Mouse pancreatic islet using Insulin Rabbit pAb (ABIN3022884, ABIN3022885, ABIN3022886 and ABIN6219279) at dilution of 1:100. (Insulin 抗体 (AA 1-110))

5 images

(1 reference)

产品编号 ABIN3022885

发货至: 中国

Datasheet as PDF

抗原 See all Insulin (INS) 抗体

Insulin (INS)
抗原表位
16

9

9

8

7

3

3

2

2

2

1

1

1

1

1

1

1

1
AA 1-110
适用
205

111

90

76

75

40

4

3

2

1

1

1

1

1

1

1

1

1
人
宿主
136

102

13

1

1

1
兔
Compatible Secondaries
克隆类型
143

113
多克隆
标记
117

21

15

8

5

5

5

5

5

5

4

4

4

4

4

4

4

4

4

4

4

3

2

2

2

2

2

2

2

2

1

1
This Insulin antibody is un-conjugated
应用范围
80

79

67

63

63

55

52

47

39

22

19

18

17

10

9

8

6

5

3

2

2

2

1

1

1

1

1

1

1

1
Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

序列

MALWMRLLPL LALLALWGPD PAAAFVNQHL CGSHLVEALY LVCGERGFFY TPKTRREAED LQVGQVELGG GPGAGSLQPL ALEGSLQKRG IVEQCCTSIC SLYQLENYCN

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human INS (NP_000198.1).

亚型

IgG
anti-Insulin (INS) (AA 46-59) antibody
INS 适用: 小鼠, 大鼠 ELISA, WB, IHC (p), FACS, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Insulin (INS) antibody
INS 适用: 人 IHC, WB, IF 宿主: 兔 Monoclonal unconjugated

anti-Insulin (INS) (AA 90-110) antibody
INS 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Insulin (INS) (AA 25-110) antibody
INS 适用: 大鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Insulin (INS) antibody
INS 适用: 人, Pig, 小鼠, Cow, 大鼠, 兔, 豚鼠, 犬, 猴, 山羊, Hamster, 马, 绵羊, Avian, Cat, 小鸡, 驴 WB 宿主: 山羊 Polyclonal unconjugated

anti-Insulin (INS) (AA 25-110) antibody
INS 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Insulin (INS) (AA 25-110) antibody
INS 适用: 人 IHC, WB, IP, ICC 宿主: 小鼠 Monoclonal H10 unconjugated

anti-Insulin (INS) (AA 25-54) antibody
INS 适用: Cow IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Insulin (INS) antibody
INS 适用: 人 IHC, ELISA 宿主: 兔 Monoclonal 1F6 unconjugated Recombinant Antibody

anti-Insulin (INS) antibody
INS 适用: 人, Pig, 小鼠, Cow, 兔 IHC, StM 宿主: 小鼠 Monoclonal rIRDN-805 unconjugated Recombinant Antibody

应用备注

WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

限制

仅限研究用
状态

Liquid

缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid freeze / thaw cycles

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
Chen, Zeng, Liu, Guo, Zhang, Chen, Lin, Wen, Zhao, Lin, Gao: "Adropin deficiency worsens HFD-induced metabolic defects." in: Cell death & disease, Vol. 8, Issue 8, pp. e3008, (2018) (PubMed).
抗原

Insulin (INS)

别名

INS (INS 产品)

别名

IDDM2 antibody, ILPR antibody, IRDN antibody, MODY10 antibody, ins1 antibody, xins antibody, ins1-a antibody, Insulin antibody, AA986540 antibody, Ins-2 antibody, InsII antibody, Mody antibody, Mody4 antibody, proinsulin antibody, zgc:109842 antibody, igf2-A antibody, ins antibody, ins-a antibody, ins-b antibody, insulin antibody, insulin precursor antibody, insulin II antibody, preproinsulin antibody, insulin L homeolog antibody, insulin S homeolog antibody, INS antibody, INS-IGF2 antibody, ins antibody, Ins antibody, PIN antibody, Ins2 antibody, ins.L antibody, ins.S antibody

背景

After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.,IDDM,IDDM1,IDDM2,ILPR,IRDN,MODY10,INS,Insulin,insulin,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,AMPK Signaling Pathway,Endocrine and metabolic diseases,Diabetes,Obesity,Immunology & Inflammation,NF-kB Signaling Pathway,Neuroscience,Stem Cells,Cardiovascular,Heart,Cardiovascular diseases,Heart disease,INS

分子量

11 kDa/21 kDa

基因ID

3630

UniProt

P01308

途径

NF-kappaB Signaling, RTK signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation