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- 抗原 See all DNMT3A 抗体
- DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))
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抗原表位
- AA 500-700
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DNMT3A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 序列
- SVTQKHIQEW GPFDLVIGGS PCNDLSIVNP ARKGLYEGTG RLFFEFYRLL HDARPKEGDD RPFFWLFENV VAMGVSDKRD ISRFLESNPV MIDAKEVSAA HRARYFWGNL PGMNRPLAST VNDKLELQEC LEHGRIAKFS KVRTITTRSN SIKQGKDQHF PVFMNEKEDI LWCTEMERVF GFPVHYTDVS NMSRLARQRL L
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 500-700 of human DNMT3A (NP_715640.2).
- 亚型
- IgG
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- 应用备注
- WB,1:500 - 1:2000,IP,1:50 - 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid freeze / thaw cycles
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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Global histone modification profiling reveals the epigenomic dynamics during malignant transformation in a four-stage breast cancer model." in: Clinical epigenetics, Vol. 8, pp. 34, (2016) (PubMed).
: "Anticancer drugs induce hypomethylation of the acetylcholinesterase promoter via a phosphorylated-p38-DNMT1-AChE pathway in apoptotic hepatocellular carcinoma cells." in: The international journal of biochemistry & cell biology, Vol. 68, pp. 21-32, (2016) (PubMed).
: "Galangin-induced down-regulation of BACE1 by epigenetic mechanisms in SH-SY5Y cells." in: Neuroscience, Vol. 294, pp. 172-81, (2015) (PubMed).
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Global histone modification profiling reveals the epigenomic dynamics during malignant transformation in a four-stage breast cancer model." in: Clinical epigenetics, Vol. 8, pp. 34, (2016) (PubMed).
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- 抗原
- DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))
- 别名
- DNMT3A (DNMT3A 产品)
- 别名
- DNMT3A antibody, DNMT3A2 antibody, M.HsaIIIA antibody, MmuIIIA antibody, dnmt3a1 antibody, dnmt6 antibody, DNA methyltransferase 3 alpha antibody, DNA methyltransferase 3A antibody, DNA (cytosine-5-)-methyltransferase 3 alpha b antibody, DNMT3A antibody, Dnmt3a antibody, dnmt3a antibody, dnmt3ab antibody
- 背景
- CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.,DNMT3A,DNMT3A2,M.HsaIIIA,TBRS,DNMT3A,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,DNA methylation,DNMT3A
- 分子量
- 16 kDa/81 kDa/101 kDa
- 基因ID
- 1788
- UniProt
- Q9Y6K1
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