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IKK alpha 抗体 (C-Term)

Name: IKK alpha 抗体 (C-Term)
Brand: antibodies-online
SKU: ABIN3022825
Availability: OutOfStock

CHUK 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

Western blot analysis of extracts of various cell lines, using CHUK antibody. (IKK alpha 抗体 (C-Term))

Immunofluorescence analysis of U-2 OS cells using CHUK antibody (ABIN3022824, ABIN3022825, ABIN3022826 and ABIN6219246) at dilution of 1:100. (IKK alpha 抗体 (C-Term))

Immunofluorescence analysis of A549 cell using CHUK antibody. (IKK alpha 抗体 (C-Term))

Immunohistochemistry of paraffin-embedded rat brain using CHUK antibody. (IKK alpha 抗体 (C-Term))

IHC (p)

Immunohistochemistry of paraffin-embedded mouse kidney using CHUK antibody. (IKK alpha 抗体 (C-Term))

IHC (p)

Immunofluorescence analysis of A549 cells using CHUK antibody. (IKK alpha 抗体 (C-Term))

Immunoprecipitation analysis of 200 μg extracts of 293T cells using 3 μg IKKα antibody (ABIN3022824, ABIN3022825, ABIN3022826 and ABIN6219246). (IKK alpha 抗体 (C-Term))

Immunofluorescence analysis of NIH/3T3 cells using CHUK antibody (ABIN3022824, ABIN3022825, ABIN3022826 and ABIN6219246) at dilution of 1:100. (IKK alpha 抗体 (C-Term))

9 images

(3 references)

产品编号 ABIN3022825

发货至: 中国

Datasheet as PDF

抗原 See all IKK alpha (CHUK) 抗体

IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))
抗原表位
15

15

12

8

8

7

7

7

7

4

4

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term
适用
119

70

54

7

6

5

4

3

3

3

2

1
人
宿主
129

12

1
兔
Compatible Secondaries
克隆类型
121

21
多克隆
标记
77

12

6

6

4

4

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2
This IKK alpha antibody is un-conjugated
应用范围
108

55

36

27

26

18

15

13

10

6

5

2

2

2

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

序列

IWHLLKIACT QSSARSLVGS SLEGAVTPQT SAWLPPTSAE HDHSLSCVVT PQDGETSAQM IEENLNCLGH LSTIIHEANE EQGNSMMNLD WSWLTE

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

纯化方法

Affinity purification

免疫原

A synthetic peptide corresponding to a sequence within amino acids 650 to the C-terminus of human IKKalpha (NP_001269.3).

亚型

IgG
anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (pSer176), (pSer177) antibody
CHUK 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (AA 646-745) antibody
CHUK 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4B8 unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (AA 646-745) antibody
CHUK 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 1F8 unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (pThr23) antibody
CHUK 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) antibody
CHUK 适用: 人 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 3G12H9 unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (pThr23) antibody
CHUK 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) antibody
CHUK 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB2159 unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (N-Term) antibody
CHUK 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (AA 551-650) antibody
CHUK 适用: 小鼠, 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (AA 84-112), (N-Term) antibody
CHUK 适用: 人 WB 宿主: 兔 Polyclonal RB41290 unconjugated

应用备注

WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200

限制

仅限研究用
状态

Liquid

缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid freeze / thaw cycles

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
Wang, Wang, Liu, Wang, Xu, Liu, Zhu, Chen, Situ, Lin: "Broadleaf Mahonia attenuates granulomatous lobular mastitis‑associated inflammation by inhibiting CCL‑5 expression in macrophages." in: International journal of molecular medicine, Vol. 41, Issue 1, pp. 340-352, (2018) (PubMed).

Gao, Yang, Yuan, Huang, Xu, Mao, Yuan, Bi: "TNFα-YAP/p65-HK2 axis mediates breast cancer cell migration." in: Oncogenesis, Vol. 6, Issue 9, pp. e383, (2017) (PubMed).

Huang, Dong, Sui, Hu, Xiong, Liao, Zhang: "MiR-223 suppresses endometrial carcinoma cells proliferation by targeting IGF-1R." in: American journal of translational research, Vol. 6, Issue 6, pp. 841-9, (2015) (PubMed).
抗原

IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))

别名

CHUK (CHUK 产品)

背景

This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.,CHUK,IKBKA,IKK-alpha,IKK1,IKKA,NFKBIKA,TCF16,IKK alpha,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Phosphorylation,Signal Transduction,Kinase,Serine/threonine kinases,PI3K-Akt Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Death Receptor Signaling Pathway,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,Cardiovascular,CHUK

分子量

84 kDa

基因ID

1147

UniProt

O15111

途径

PI3K-Akt Signaling, NF-kappaB Signaling, RTK signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins