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POLH 抗体 (AA 20-320)

This anti-POLH antibody is a 兔 多克隆 antibody detecting POLH in WB 和 IF. Suitable for 人.
产品编号 ABIN3022621
发货至: 中国

Quick Overview for POLH 抗体 (AA 20-320) (ABIN3022621)

抗原

See all POLH 抗体
POLH (Polymerase (DNA Directed), eta (POLH))

适用

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宿主

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克隆类型

  • 45
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多克隆

标记

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This POLH antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    AA 20-320

    序列

    QVEQRQNPHL RNKPCAVVQY KSWKGGGIIA VSYEARAFGV TRSMWADDAK KLCPDLLLAQ VRESRGKANL TKYREASVEV MEIMSRFAVI ERASIDEAYV DLTSAVQERL QKLQGQPISA DLLPSTYIEG LPQGPTTAEE TVQKEGMRKQ GLFQWLDSLQ IDNLTSPDLQ LTVGAVIVEE MRAAIERETG FQCSAGISHN KVLAKLACGL NKPNRQTLVS HGSVPQLFSQ MPIRKIRSLG GKLGASVIEI LGIEYMGELT QFTESQLQSH FGEKNGSWLY AMCRGIEHDP VKPRQLPKTI G

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 20-320 of human DNA polymerase eta (NP_006493.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    POLH (Polymerase (DNA Directed), eta (POLH))

    别名

    POLH

    背景

    This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA, when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene.,POLH,RAD30,RAD30A,XP-V,XPV,Epigenetics & Nuclear Signaling,POLH

    分子量

    46 kDa/78 kDa

    基因ID

    5429

    UniProt

    Q9Y253

    途径

    DNA Damage Repair
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