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KEAP1 抗体 (AA 325-624)

KEAP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3022609
发货至: 中国
  • 抗原 See all KEAP1 抗体
    KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
    抗原表位
    • 15
    • 15
    • 12
    • 11
    • 10
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 325-624
    适用
    • 86
    • 61
    • 37
    • 23
    • 18
    • 8
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    宿主
    • 82
    • 9
    • 1
    克隆类型
    • 81
    • 11
    多克隆
    标记
    • 44
    • 8
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KEAP1 antibody is un-conjugated
    应用范围
    • 75
    • 37
    • 30
    • 26
    • 26
    • 16
    • 8
    • 7
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    序列
    GRLIYTAGGY FRQSLSYLEA YNPSDGTWLR LADLQVPRSG LAGCVVGGLL YAVGGRNNSP DGNTDSSALD CYNPMTNQWS PCAPMSVPRN RIGVGVIDGH IYAVGGSHGC IHHNSVERYE PERDEWHLVA PMLTRRIGVG VAVLNRLLYA VGGFDGTNRL NSAECYYPER NEWRMITAMN TIRSGAGVCV LHNCIYAAGG YDGQDQLNSV ERYDVETETW TFVAPMKHRR SALGITVHQG RIYVLGGYDG HTFLDSVECY DPDTDTWSEV TRMTSGRSGV GVAVTMEPCR KQIDQQNCTC
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 325-624 of human KEAP1 (NP_036421.2).
    亚型
    IgG
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze / thaw cycles
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Chen, Li, Fan, Cao, Yao, Xu: "Selenium antagonizes cadmium-induced apoptosis in chicken spleen but not involving Nrf2-regulated antioxidant response." in: Ecotoxicology and environmental safety, Vol. 145, pp. 503-510, (2017) (PubMed).

    Xu, Zhang, Lu, Deng, Zhao, Zhao, Zhao: "Prevention of Hippocampal Neuronal Damage and Cognitive Function Deficits in Vascular Dementia by Dextromethorphan." in: Molecular neurobiology, Vol. 53, Issue 5, pp. 3494-502, (2016) (PubMed).

  • 抗原
    KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
    别名
    KEAP1 (KEAP1 产品)
    背景
    This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.,KEAP1,INrf2,KLHL19,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,KEAP1
    分子量
    69 kDa
    基因ID
    9817
    UniProt
    Q14145
    途径
    Maintenance of Protein Location
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