PIG4 antibody, SAA antibody, SAA2 antibody, TP53I4 antibody, zgc:103580 antibody, SAA1 antibody, Saa-1 antibody, Saa2 antibody, serum amyloid A1 antibody, serum amyloid A antibody, amyloid protein A antibody, serum amyloid A protein antibody, serum amyloid a protein antibody, serum amyloid A 1 antibody, serum amyloid protein A antibody, SAA1 antibody, saa antibody, LOC694827 antibody, Sden_2438 antibody, Mmc1_0571 antibody, Riean_0971 antibody, Saa1 antibody, LOC100009168 antibody, LOC101120204 antibody
背景
This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11.,SAA1,PIG4,SAA,SAA2,TP53I4,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Immunology & Inflammation,Cytokines,Cell Intrinsic Innate Immunity Signaling Pathway,Cardiovascular,Lipids,Lipoproteins/Apolipoproteins,SAA1