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- 抗原 See all NFATC1 抗体
- NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))
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抗原表位
- AA 20-300
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NFATC1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 序列
- VFGRGETLGP APRAGGTMKS AEEEHYGYAS SNVSPALPLP TAHSTLPAPC HNLQTSTPGI IPPADHPSGY GAALDGGPAG YFLSSGHTRP DGAPALESPR IEITSCLGLY HNNNQFFHDV EVEDVLPSSK RSPSTATLSL PSLEAYRDPS CLSPASSLSS RSCNSEASSY ESNYSYPYAS PQTSPWQSPC VSPKTTDPEE GFPRGLGACT LLGSPRHSPS TSPRASVTEE SWLGARSSRP ASPCNKRKYS LNGRQPPYSP HHSPTPSPHG SPRVSVTDDS W
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human NFAT2 (NP_765978.1).
- 亚型
- IgG
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- 应用备注
- WB,1:500 - 1:3000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid freeze / thaw cycles
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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Berberine inhibits IL-21/IL-21R mediated inflammatory proliferation of fibroblast-like synoviocytes through the attenuation of PI3K/Akt signaling pathway and ameliorates IL-21 mediated ..." in: Cytokine, Vol. 106, pp. 54-66, (2018) (PubMed).
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Berberine inhibits IL-21/IL-21R mediated inflammatory proliferation of fibroblast-like synoviocytes through the attenuation of PI3K/Akt signaling pathway and ameliorates IL-21 mediated ..." in: Cytokine, Vol. 106, pp. 54-66, (2018) (PubMed).
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- 抗原
- NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))
- 别名
- NFATC1 (NFATC1 产品)
- 别名
- nf-atc antibody, nfat2 antibody, nfatc antibody, si:ch211-198c22.2 antibody, NFATC1 antibody, 2210017P03Rik antibody, AI449492 antibody, AV076380 antibody, NF-ATc antibody, NFAT2 antibody, NFATc antibody, Nfatcb antibody, NF-ATC antibody, NF-ATc1 antibody, NFAT antibody, NFATmac antibody, nuclear factor of activated T-cells 1 antibody, nuclear factor of activated T-cells 1 L homeolog antibody, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 antibody, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 antibody, NFATC1 antibody, nfatc1.L antibody, nfatc1 antibody, Nfatc1 antibody
- 背景
- The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.,NF-ATC,NF-ATc1.2,NFAT2,NFATc,NFATC1,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,MAPK-JNK Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,Cardiovascular,Heart,Cardiogenesis,NFATC1
- 分子量
- 38 kDa/74- 88 kDa/100-101 kDa
- 基因ID
- 4772
- UniProt
- O95644
- 途径
- RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway
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