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CBS 抗体 (AA 252-551)

CBS 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3021959
发货至: 中国
  • 抗原 See all CBS 抗体
    CBS (Cystathionine-beta-Synthase (CBS))
    抗原表位
    • 15
    • 9
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 252-551
    适用
    • 54
    • 41
    • 12
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 65
    • 9
    克隆类型
    • 59
    • 15
    多克隆
    标记
    • 39
    • 6
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CBS antibody is un-conjugated
    应用范围
    • 56
    • 31
    • 17
    • 14
    • 14
    • 14
    • 13
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    序列
    VASVGTGGTI TGIARKLKEK CPGCRIIGVD PEGSILAEPE ELNQTEQTTY EVEGIGYDFI PTVLDRTVVD KWFKSNDEEA FTFARMLIAQ EGLLCGGSAG STVAVAVKAA QELQEGQRCV VILPDSVRNY MTKFLSDRWM LQKGFLKEED LTEKKPWWWH LRVQELGLSA PLTVLPTITC GHTIEILREK GFDQAPVVDE AGVILGMVTL GNMLSSLLAG KVQPSDQVGK VIYKQFKQIR LTDTLGRLSH ILEMDHFALV VHEQIQYHST GKSSQRQMVF GVVTAIDLLN FVAAQERDQK
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 252-551 of human CBS (NP_000062.1).
    亚型
    IgG
    Top Product
    Discover our top product CBS Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze / thaw cycles
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Niu, Wang, Qian, Wang, Wu, Chen, Yan: "Allosteric control of human cystathionine β-synthase activity by a redox active disulfide bond." in: The Journal of biological chemistry, Vol. 293, Issue 7, pp. 2523-2533, (2018) (PubMed).

    Seale, Ha, Hashimoto, Berry: "Relationship between selenoprotein P and selenocysteine lyase: Insights into selenium metabolism." in: Free radical biology & medicine, Vol. 127, pp. 182-189, (2018) (PubMed).

  • 抗原
    CBS (Cystathionine-beta-Synthase (CBS))
    别名
    CBS (CBS 产品)
    别名
    hip4 antibody, GB12529 antibody, CBS antibody, DDBDRAFT_0189727 antibody, DDBDRAFT_0191292 antibody, DDB_0189727 antibody, DDB_0191292 antibody, cbs antibody, AI047524 antibody, AI303044 antibody, HIP4 antibody, cb442 antibody, wu:fb37g05 antibody, wu:fm61c07 antibody, wu:fq06c06 antibody, zgc:113704 antibody, cystathionine-beta-synthase L homeolog antibody, cystathionine-beta-synthase antibody, cystathionine beta-synthase antibody, cystathionine beta-synthase CBS antibody, cystathionine beta synthase antibody, cystathionine-beta-synthase S homeolog antibody, cystathionine-beta-synthase b antibody, cbs.L antibody, cbs antibody, Cbs antibody, CBS antibody, CNA06170 antibody, Tb11.02.5400 antibody, cysB antibody, LOC100635325 antibody, cbs.S antibody, cbsb antibody
    背景
    The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. This gene is a major contributor to cellular hydrogen sulfide production. Multiple alternatively spliced transcript variants have been found for this gene.,CBS,HIP4,Cancer,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,CBS
    分子量
    60 kDa/61 kDa
    基因ID
    875
    UniProt
    P35520
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