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- 抗原 See all SOD2 抗体
- SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))
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抗原表位
- AA 25-222
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SOD2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 序列
- KHSLPDLPYD YGALEPHINA QIMQLHHSKH HAAYVNNLNV TEEKYQEALA KGDVTAQIAL QPALKFNGGG HINHSIFWTN LSPNGGGEPK GELLEAIKRD FGSFDKFKEK LTAASVGVQG SGWGWLGFNK ERGHLQIAAC PNQDPLQGTT GLIPLLGIDV WEHAYYLQYK NVRPDYLKAI WNVINWENVT ERYMACKK
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 25-222 of human SOD2 (NP_000627.2).
- 亚型
- IgG
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid freeze / thaw cycles
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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Celastrol ameliorates liver metabolic damage caused by a high-fat diet through Sirt1." in: Molecular metabolism, Vol. 6, Issue 1, pp. 138-147, (2018) (PubMed).
: "Leucine reduces reactive oxygen species levels via an energy metabolism switch by activation of the mTOR-HIF-1α pathway in porcine intestinal epithelial cells." in: The international journal of biochemistry & cell biology, Vol. 89, pp. 42-56, (2017) (PubMed).
: "Ganoderma lucidum polysaccharide peptide prevents renal ischemia reperfusion injury via counteracting oxidative stress." in: Scientific reports, Vol. 5, pp. 16910, (2016) (PubMed).
: "Chronic Exercise Training Improved Aortic Endothelial and Mitochondrial Function via an AMPKα2-Dependent Manner." in: Frontiers in physiology, Vol. 7, pp. 631, (2016) (PubMed).
: "Mst1 regulates hepatic lipid metabolism by inhibiting Sirt1 ubiquitination in mice." in: Biochemical and biophysical research communications, Vol. 471, Issue 4, pp. 444-9, (2016) (PubMed).
: "Mycobacterium tuberculosis Rv2185c contributes to nuclear factor-κB activation." in: Molecular immunology, Vol. 66, Issue 2, pp. 147-53, (2015) (PubMed).
: "Rejuvenation of MPTP-induced human neural precursor cell senescence by activating autophagy." in: Biochemical and biophysical research communications, Vol. 464, Issue 2, pp. 526-33, (2015) (PubMed).
: "Cobalt protoporphyrin induces HO-1 expression mediated partially by FOXO1 and reduces mitochondria-derived reactive oxygen species production." in: PLoS ONE, Vol. 8, Issue 11, pp. e80521, (2014) (PubMed).
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Celastrol ameliorates liver metabolic damage caused by a high-fat diet through Sirt1." in: Molecular metabolism, Vol. 6, Issue 1, pp. 138-147, (2018) (PubMed).
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- 抗原
- SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))
- 别名
- SOD2 (SOD2 产品)
- 别名
- LOC100101896 antibody, MNSOD antibody, GB14346 antibody, sod2 antibody, MGC88869 antibody, Sod2 antibody, CG8905 antibody, Dmel\\CG8905 antibody, Mito SOD antibody, Mn SOD antibody, Mn-SOD antibody, Mn-SOD2 antibody, MnSOD antibody, MnSODII antibody, Mn[2+]SOD antibody, SOD antibody, SOD-2 antibody, SOD2 antibody, Sod-2 antibody, dSOD2 antibody, mitSOD2 antibody, mnSOD antibody, IPOB antibody, MVCD6 antibody, cb463 antibody, wu:fj33b01 antibody, zgc:73051 antibody, MnSOD antibody, manganese superoxide dismutase antibody, superoxide dismutase 2, mitochondrial antibody, superoxide dismutase 2 antibody, Mn superoxide dismutase antibody, Superoxide dismutase 2 (Mn) antibody, superoxide dismutase 2 L homeolog antibody, BDBG_07234 antibody, LOC100101896 antibody, MNSOD antibody, Sod2 antibody, sod2 antibody, LbMnSOD4 antibody, SOD2 antibody, LOC100282741 antibody, SOD-2 antibody, sod2.L antibody
- 背景
- This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1.,IPO-B,IPOB,MNSOD,MVCD6,Mn-SOD,SOD2,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Hypoxia,SOD2
- 分子量
- 18 kDa/19 kDa/20 kDa/24 kDa
- 基因ID
- 6648
- UniProt
- P04179
- 途径
- Sensory Perception of Sound, Transition Metal Ion Homeostasis, Negative Regulation of intrinsic apoptotic Signaling
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