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- 抗原 See all CD86 抗体
- CD86
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抗原表位
- AA 30-247
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CD86 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 序列
- AYFNETADLP CQFANSQNQS LSELVVFWQD QENLVLNEVY LGKEKFDSVH SKYMGRTSFD SDSWTLRLHN LQIKDKGLYQ CIIHHKKPTG MIRIHQMNSE LSVLANFSQP EIVPISNITE NVYINLTCSS IHGYPEPKKM SVLLRTKNST IEYDGIMQKS QDNVTELYDV SISLSVSFPD VTSNMTIFCI LETDKTRLLS SPFSIELEDP QPPPDHIP
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 30-247 of human CD86 (NP_787058.4).
- 亚型
- IgG
- Top Product
- Discover our top product CD86 Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid freeze / thaw cycles
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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The observed difference of RAW264.7 macrophage phenotype on mineralized collagen and hydroxyapatite." in: Biomedical materials (Bristol, England), Vol. 13, Issue 4, pp. 041001, (2018) (PubMed).
: "Surfactant protein D regulates murine testicular immune milieu and sperm functions." in: American journal of reproductive immunology (New York, N.Y. : 1989), Vol. 77, Issue 3, (2017) (PubMed).
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The observed difference of RAW264.7 macrophage phenotype on mineralized collagen and hydroxyapatite." in: Biomedical materials (Bristol, England), Vol. 13, Issue 4, pp. 041001, (2018) (PubMed).
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- 抗原
- CD86
- 别名
- CD86 (CD86 产品)
- 别名
- B7-2 antibody, B7.2 antibody, B70 antibody, CD28LG2 antibody, LAB72 antibody, B7 antibody, CLS1 antibody, Cd28l2 antibody, ETC-1 antibody, Ly-58 antibody, Ly58 antibody, MB7 antibody, MB7-2 antibody, TS/A-2 antibody, CD86 molecule antibody, CD86 antigen antibody, integrin subunit alpha 2b antibody, CD86 antibody, Cd86 antibody, Itga2b antibody
- 背景
- This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.,B7-2,B7.2,B70,CD28LG2,LAB72,CD86,Immunology & Inflammation,CD markers,Stem Cells,Hematopoietic Progenitors,CD86
- 分子量
- 12 kDa/24 kDa/28 kDa/31 kDa/37 kDa
- 基因ID
- 942
- UniProt
- P42081
- 途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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