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PML 抗体 (AA 300-600)

Name: PML 抗体 (AA 300-600)
Brand: antibodies-online
SKU: ABIN3021659
Availability: OutOfStock

PML 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

Western blot analysis of extracts from normal (control) and PML knockout (KO) HeLa cells, using PML antibody (ABIN3021658, ABIN3021659, ABIN3021660, ABIN1513388 and ABIN1514534) at 1:1000 dilution. (PML 抗体 (AA 300-600))

Immunofluorescence analysis of HeLa cell using PML antibody. (PML 抗体 (AA 300-600))

Western blot analysis of extracts of various cell lines, using PML antibody. (PML 抗体 (AA 300-600))

3 images

(1 reference)

产品编号 ABIN3021659

发货至: 中国

Datasheet as PDF

抗原 See all PML 抗体

PML (Promyelocytic Leukemia (PML))
抗原表位
13

8

5

4

3

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 300-600
适用
69

23

20

2

2

2

1

1

1
人
宿主
62

10
兔
Compatible Secondaries
克隆类型
62

10
多克隆
标记
44

5

4

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This PML antibody is un-conjugated
应用范围
53

26

18

17

12

11

8

7

5

3

2

2

2

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

序列

AVDARYQRDY EEMASRLGRL DAVLQRIRTG SALVQRMKCY ASDQEVLDMH GFLRQALCRL RQEEPQSLQA AVRTDGFDEF KVRLQDLSSC ITQGKDAAVS KKASPEAAST PRDPIDVDLD VSNTTTAQKR KCSQTQCPRK VIKMESEEGK EARLARSSPE QPRPSTSKAV SPPHLDGPPS PRSPVIGSEV FLPNSNHVAS GAGEAEERVV VISSSEDSDA ENSCMEPMET AEPQSSPAHS SPAHSSPAHS SPVQSLLRAQ GASSLPCGTY HPPAWPPHQP AEQAATPDAE PHSEPPDHQE R

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 300-600 of human PML (NP_150253.2).

亚型

IgG

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anti-Promyelocytic Leukemia (PML) (N-Term) antibody
PML 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated

anti-Promyelocytic Leukemia (PML) (AA 470-499), (Sumoylation Site) antibody
PML 适用: 人 WB, IHC, IF, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Promyelocytic Leukemia (PML) (C-Term) antibody
PML 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 犬, Pig, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Promyelocytic Leukemia (PML) (AA 411-510) antibody
PML 适用: 人 WB, IF, ELISA 宿主: 小鼠 Monoclonal 2B10 unconjugated

anti-Promyelocytic Leukemia (PML) (C-Term) antibody
PML 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated

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PML 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB2570 unconjugated

anti-Promyelocytic Leukemia (PML) (N-Term) antibody
PML 适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Promyelocytic Leukemia (PML) (AA 588-637) antibody
PML 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Promyelocytic Leukemia (PML) (AA 59-239) antibody
PML 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB,1:500 - 1:2000,IHC,1:50 - 1:200

限制

仅限研究用
状态

Liquid

缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid freeze / thaw cycles

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
Li, Zhong, Liu, Yu, Chen, Wang, Shi, Yuan: "Evidence for Kaposi Sarcoma Originating from Mesenchymal Stem Cell through KSHV-induced Mesenchymal-to-Endothelial Transition." in: Cancer research, Vol. 78, Issue 1, pp. 230-245, (2018) (PubMed).
抗原

PML (Promyelocytic Leukemia (PML))

别名

PML (PML 产品)

别名

MYL antibody, PP8675 antibody, RNF71 antibody, TRIM19 antibody, 1200009E24Rik antibody, AI661194 antibody, Trim19 antibody, RGD1562602 antibody, PML antibody, promyelocytic leukemia antibody, PML antibody, Pml antibody

背景

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions, all variants encode the same N-terminus. Alternatively spliced transcript variants encoding different isoforms have been identified.,MYL,PP8675,RNF71,TRIM19,PML,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Cell Biology & Developmental Biology,Apoptosis,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,Endocrine & Metabolism,Cardiovascular,Angiogenesis,PML

分子量

47-48 kDa/62-97 kDa

基因ID

5371

UniProt

P29590

途径

p53 Pathway, Retinoic Acid Receptor Signaling Pathway, Maintenance of Protein Location, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus