Glutathione Peroxidase 1 抗体 (AA 50-203)
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- 抗原 See all Glutathione Peroxidase 1 (GPX1) 抗体
- Glutathione Peroxidase 1 (GPX1)
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抗原表位
- AA 50-203
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Glutathione Peroxidase 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 序列
- GTTVRDYTQM NELQRRLGPR GLVVLGFPCN QFGHQENAKN EEILNSLKYV RPGGGFEPNF MLFEKCEVNG AGAHPLFAFL REALPAPSDD ATALMTDPKL ITWSPVCRND VAWNFEKFLV GPDGVPLRRY SRRFQTIDIE PDIEALLSQG PSCA
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 50-203 of human GPX1 (NP_000572.2).
- 亚型
- IgG
- Top Product
- Discover our top product GPX1 Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid freeze / thaw cycles
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- Glutathione Peroxidase 1 (GPX1)
- 别名
- GPX1 (GPX1 产品)
- 背景
- This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.,GPXD,GSHPX1,GPX1,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Neuroscience,Neurodegenerative Diseases,GPX1
- 分子量
- 10 kDa/22 kDa
- 基因ID
- 2876
- UniProt
- P07203
- 途径
- Thyroid Hormone Synthesis, Sensory Perception of Sound, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome
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