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SMAD1 抗体 (AA 20-240)

SMAD1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3021439
发货至: 中国
  • 抗原 See all SMAD1 抗体
    SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))
    抗原表位
    • 23
    • 23
    • 23
    • 15
    • 15
    • 13
    • 11
    • 9
    • 8
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 20-240
    适用
    • 209
    • 129
    • 93
    • 9
    • 8
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    宿主
    • 206
    • 18
    克隆类型
    • 200
    • 25
    多克隆
    标记
    • 101
    • 19
    • 13
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    This SMAD1 antibody is un-conjugated
    应用范围
    • 173
    • 90
    • 53
    • 52
    • 42
    • 32
    • 20
    • 17
    • 12
    • 12
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    序列
    WKQGDEEEKW AEKAVDALVK KLKKKKGAME ELEKALSCPG QPSNCVTIPR SLDGRLQVSH RKGLPHVIYC RVWRWPDLQS HHELKPLECC EFPFGSKQKE VCINPYHYKR VESPVLPPVL VPRHSEYNPQ HSLLAQFRNL GQNEPHMPLN ATFPDSFQQP NSHPFPHSPN SSYPNSPGSS SSTYPHSPTS SDPGSPFQMP ADTPPPAYLP PEDPMTQDGS Q
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 20-240 of human Smad1 (NP_001003688.1).
    亚型
    IgG
    Top Product
    Discover our top product SMAD1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze / thaw cycles
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Kong, Liang, Chen, Yang, Liu, Li, Feng, Wu, Liu, Tang, Yu, Ou, Lu, Yan: "Hyaluronan negatively regulates vascular calcification involving BMP2 signaling." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 98, Issue 10, pp. 1320-1332, (2018) (PubMed).

  • 抗原
    SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))
    别名
    SMAD1 (SMAD1 产品)
    别名
    MLP antibody, Xmad1 antibody, Xsmad1 antibody, bsp1 antibody, jv4-1 antibody, jv41 antibody, madh1 antibody, madr1 antibody, smad-1 antibody, MADH1 antibody, fb39h09 antibody, wu:fb39h09 antibody, wu:fb97e04 antibody, 2/23 antibody, CG12399 antibody, Dmel\\CG12399 antibody, E(zen)2 antibody, En(vvl) antibody, MAD antibody, Mat antibody, P-Mad antibody, P-mad antibody, PMad antibody, Smad antibody, Smad1 antibody, apg antibody, c28 antibody, dMAD antibody, dMad antibody, l(2)K00237 antibody, l(2)k00237 antibody, mad antibody, p-Mad antibody, pMAD antibody, pMad antibody, pSmad antibody, BSP-1 antibody, BSP1 antibody, JV4-1 antibody, JV41 antibody, MADR1 antibody, AI528653 antibody, Madh1 antibody, Madr1 antibody, Mlp1 antibody, MusMLP antibody, smad1 antibody, xmad antibody, SMAD family member 1 antibody, Mothers against dpp antibody, SMAD family member 1 L homeolog antibody, smad1 antibody, SMAD1 antibody, Mad antibody, Smad1 antibody, smad1.L antibody
    背景
    The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed.,BSP-1,BSP1,JV4-1,JV41,MADH1,MADR1,Smad1,SMAD1,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,TGF-b-Smad Signaling Pathway,ESC Pluripotency and Differentiation,Immunology & Inflammation,Stem Cells,SMADs,SMAD1
    分子量
    15 kDa/52 kDa
    基因ID
    4086
    UniProt
    Q15797
    途径
    Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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