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- 抗原 See all FAM3B 抗体
- FAM3B (Family with Sequence Similarity 3, Member B (FAM3B))
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抗原表位
- AA 30-235
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FAM3B antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- 序列
- ELIPDAPLSS AAYSIRSIGE RPVLKAPVPK RQKCDHWTPC PSDTYAYRLL SGGGRSKYAK ICFEDNLLMG EQLGNVARGI NIAIVNYVTG NVTATRCFDM YEGDNSGPMT KFIQSAAPKS LLFMVTYDDG STRLNNDAKN AIEALGSKEI RNMKFRSSWV FIAAKGLELP SEIQREKINH SDAKNNRYSG WPAEIQIEGC IPKERS
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 30-235 of human FAM3B (NP_478066.3).
- 亚型
- IgG
- Top Product
- Discover our top product FAM3B Primary Antibody
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anti-Family with Sequence Similarity 3, Member B (FAM3B) (AA 1-235) antibody
FAM3B 适用: 人 WB, ELISA, IP, IHC (p) 宿主: 小鼠 Monoclonal 1E7 unconjugated
anti-Family with Sequence Similarity 3, Member B (FAM3B) antibodyFAM3B 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 3, Member B (FAM3B) (AA 1-100) antibodyFAM3B 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 3, Member B (FAM3B) (AA 31-235) antibodyFAM3B 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 3, Member B (FAM3B) (C-Term) antibodyFAM3B 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 3, Member B (FAM3B) (AA 1-235) antibodyFAM3B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 3, Member B (FAM3B) (AA 24-51), (N-Term) antibodyFAM3B 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB21063 unconjugated
anti-Family with Sequence Similarity 3, Member B (FAM3B) (AA 30-235) antibodyFAM3B 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 3, Member B (FAM3B) antibodyFAM3B 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 3, Member B (FAM3B) antibodyFAM3B 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IHC,1:100 - 1:200,IF,1:100 - 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid freeze / thaw cycles
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- FAM3B (Family with Sequence Similarity 3, Member B (FAM3B))
- 别名
- FAM3B (FAM3B 产品)
- 别名
- 2-21 antibody, C21orf11 antibody, C21orf76 antibody, ORF9 antibody, PANDER antibody, 9030624C24Rik antibody, D16Jhu19e antibody, Pander antibody, RGD1311662 antibody, family with sequence similarity 3 member B antibody, family with sequence similarity 3, member B antibody, FAM3B antibody, Fam3b antibody
- 物质类
- Viral Protein
- 背景
- FAM3B, also known as Pancreatic-derived factor (PANDER), is an islet-specific secreted cytokine specifically expressed at high levels in the islets of Langerhans of the endocrine pancreas. FAM3B can induce apoptosis of alpha and beta cells in a dose- and time-dependent manner. Previous studies showed that FAM3B regulates glucose and lipid metabolism through interaction with liver and endocrine pancreas. FAM3B silencing activates both extrinsic and intrinsic apoptotic pathways. In general, silencing FAM3B promoted p53 phosphorylation and induced p53 accumulation by decreasing Mdm2 expression, which resulted in apoptotic cell death.,FAM3B,2-21,C21orf11,C21orf76,ORF9,PANDER,PRED44,Endocrine & Metabolism,Endocrine and metabolic diseases,Diabetes,Metabolic disorders,Obesity,Immunology & Inflammation,Cytokines,Cell Intrinsic Innate Immunity Signaling Pathway,FAM3B
- 分子量
- 20 kDa/25 kDa/30 kDa
- 基因ID
- 54097
- UniProt
- P58499
- 途径
- Hormone Transport
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