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TPMT 抗体 (AA 1-245)
TPMT
适用: 人
WB, IF
宿主: 兔
Polyclonal
unconjugated
TPMT抗体详情
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抗原
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TPMT
(Thiopurine S-Methyltransferase (TPMT))
抗原表位
All epitopes for TPMT 抗体
AA 1-245
适用
All reactivities for TPMT 抗体
人
宿主
All hosts for TPMT 抗体
兔
克隆类型
All clonalities for TPMT 抗体
多克隆
标记
All conjugates for TPMT 抗体
This TPMT antibody is un-conjugated
应用范围
All applications for TPMT 抗体
Western Blotting (WB), Immunofluorescence (IF)
序列
MDGTRTSLDI EEYSDTEVQK NQVLTLEEWQ DKWVNGKTAF HQEQGHQLLK KHLDTFLKGK SGLRVFFPLC GKAVEMKWFA DRGHSVVGVE ISELGIQEFF TEQNLSYSEE PITEIPGTKV FKSSSGNISL YCCSIFDLPR TNIGKFDMIW DRGALVAINP GDRKCYADTM FSLLGKKFQY LLCVLSYDPT KHPGPPFYVP HAEIERLFGK ICNIRCLEKV DAFEERHKSW GIDCLFEKLY LLTEK
交叉反应
人
产品特性
Polyclonal Antibodies
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-245 of human TPMT (NP_000358.1).
亚型
IgG
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Alternatives
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使用细节
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应用备注
WB,1:500 - 1:2000,IF,1:10 - 1:100
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid freeze / thaw cycles
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
TPMT目标详情
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抗原
TPMT
(Thiopurine S-Methyltransferase (TPMT))
别名
TPMT (TPMT 产品 )
别名
MGC84277 antibody, AW106912 antibody, NHLRC1 antibody, thiopurine S-methyltransferase L homeolog antibody, thiopurine S-methyltransferase, tandem duplicate 2 antibody, thiopurine S-methyltransferase TpmT antibody, thiopurine S-methyltransferase antibody, Thiopurine S-methyltransferase antibody, thiopurine methyltransferase antibody, tpmt.L antibody, tpmt.2 antibody, tpmT antibody, MCA0794 antibody, Pnap_4948 antibody, Hhal_1383 antibody, TK90_1044 antibody, Slit_1144 antibody, Tint_0842 antibody, Fbal_3334 antibody, Celly_3188 antibody, Weevi_1737 antibody, Psefu_2696 antibody, Metme_3860 antibody, Tpmt antibody, TPMT antibody
背景
This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X.,TPMT,TPMTD,Signal Transduction,Endocrine & Metabolism,Drug metabolism,TPMT
分子量
28 kDa
基因ID
7172
UniProt
P51580
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