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- 抗原 See all SOX2 抗体
- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
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抗原表位
- AA 1-140
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SOX2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- 序列
- MYNMMETELK PPGPQQTSGG GGGNSTAAAA GGNQKNSPDR VKRPMNAFMV WSRGQRRKMA QENPKMHNSE ISKRLGAEWK LLSETEKRPF IDEAKRLRAL HMKEHPDYKY RPRRKTKTLM KKDKYTLPGG LLAPGGNSMA
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human SOX2 (NP_003097.1).
- 亚型
- IgG
- Top Product
- Discover our top product SOX2 Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid freeze / thaw cycles
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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FOXM1 contributes to taxane resistance by regulating UHRF1-controlled cancer cell stemness." in: Cell death & disease, Vol. 9, Issue 5, pp. 562, (2018) (PubMed).
: "NSPc1 promotes cancer stem cell self-renewal by repressing the synthesis of all-trans retinoic acid via targeting RDH16 in malignant glioma." in: Oncogene, Vol. 36, Issue 33, pp. 4706-4718, (2017) (PubMed).
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FOXM1 contributes to taxane resistance by regulating UHRF1-controlled cancer cell stemness." in: Cell death & disease, Vol. 9, Issue 5, pp. 562, (2018) (PubMed).
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- 抗原
- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
- 别名
- SOX2 (SOX2 产品)
- 别名
- ANOP3 antibody, MCOPS3 antibody, RGD1565646 antibody, Sox-2 antibody, lcc antibody, ysb antibody, cb236 antibody, wu:fb83g04 antibody, wu:fc14d07 antibody, zgc:65860 antibody, zgc:77389 antibody, SRY-box2 antibody, Xsox-2 antibody, anop3 antibody, mcops3 antibody, sox-2 antibody, SRY-box 2 antibody, SRY box 2 antibody, SRY (sex determining region Y)-box 2 antibody, SRY-box 2 S homeolog antibody, SOX2 antibody, Sox2 antibody, sox2 antibody, sox2.S antibody
- 背景
- This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).,ANOP3,MCOPS3,SOX2,SRY-box 2,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,Cell Biology & Developmental Biology,ESC Pluripotency and Differentiation,Neuroscience,Cell Type Marker,Stem Cells,Embryonic Stem Cells,Germline Stem Cells,Neural Stem Cell marker,SOX2
- 分子量
- 34 kDa
- 基因ID
- 6657
- UniProt
- P48431
- 途径
- Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
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