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Clathrin Heavy Chain (CLTC) 抗体

CLTC 适用: 人, 小鼠, 大鼠, Cow, Pig WB, ELISA, FACS, IP, ICC 宿主: 小鼠 Monoclonal BF-06 unconjugated
产品编号 ABIN302098
发货至: 中国
  • 抗原 See all Clathrin Heavy Chain (CLTC) 抗体
    Clathrin Heavy Chain (CLTC)
    适用
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    人, 小鼠, 大鼠, Cow, Pig
    宿主
    • 65
    • 19
    • 5
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    小鼠
    克隆类型
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    • 27
    单克隆
    标记
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    非结合性
    应用范围
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    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)
    特异性
    The antibody BF-06 recognizes clathrin heavy chain, an ubiquitously expressed 180 kDa intracellular protein involved in receptor-mediated endocytosis.
    交叉反应 (详细)
    Human, Porcine, Mouse, Rat, Bovine, Other not determined
    纯化方法
    Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).
    纯度
    > 95 % (by SDS-PAGE)
    克隆位点
    BF-06
    亚型
    IgM
    Top Product
    Discover our top product CLTC Primary Antibody
  • 应用备注
    Flow cytometry: Recommended dilution: 2-5 μg/mL, positive control: human blood leukocytes. Intracellular staining.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • Mac?rek, Zíková, Dráberová, Dráber: "Monoclonal antibody BF-06 against the heavy chain of clathrin." in: Folia biologica, Vol. 49, Issue 6, pp. 238-40, (2004) (PubMed).

  • 抗原
    Clathrin Heavy Chain (CLTC)
    别名
    Clathrin heavy chain (CLTC 产品)
    背景
    Clathrin heavy chain,Clathrin is a submembrane protein that polymerizes into coat-like lattices, which results in membrane invagination. The basic oligomers are composed of three clathrin heavy chain (180 kDa) and three light chain (30 kDa) subunits and the process of polymerization is dynamically regulated by the light chains. Interaction of clathrin with the plasma membrane is mediated by adaptor proteins (AP1-4) specific for different cellular compartments. Another proteins, such as endophilin, epsin and amphiphysin are involved in membrane invagination and clathrin rearrangements. Finally, dynamin functions at the fission stage of clathrin-mediated endocytosis.,CHC, CLHC, MRD56
    基因ID
    1213
    UniProt
    Q00610
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