AHNAK 抗体 (N-Term)
(1 reference)-
- 抗原 See all AHNAK 抗体
- AHNAK (AHNAK Nucleoprotein (AHNAK))
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抗原表位
- N-Term
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适用
- 人, 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This AHNAK antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- The mouse monoclonal antibody EM-09 reacts with AHNAK1, a 700 kDa multi-functional adaptor protein expressed mainly in epithelial cell, various types of muscle cells and immune cells.
- 交叉反应 （详细）
- Human, Mouse
- 纯化方法
- Purified by protein-A affinity chromatography.
- 纯度
- > 95 % (by SDS-PAGE)
- 免疫原
- Bacterially expressed fragment of N-terminal domain of human AHNAK1.
- 克隆位点
- EM-09
- 亚型
- IgG1
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anti-AHNAK Nucleoprotein (AHNAK) (AA 1-300) antibody
AHNAK 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-AHNAK Nucleoprotein (AHNAK) (AA 1-100) antibodyAHNAK 适用: 人 ELISA, WB, IP 宿主: 小鼠 Monoclonal 3G7 unconjugated
anti-AHNAK Nucleoprotein (AHNAK) (AA 5689-5801) antibodyAHNAK 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-AHNAK Nucleoprotein (AHNAK) antibodyAHNAK 适用: 人 ICC, DB 宿主: 小鼠 Monoclonal 2014C3a unconjugated
anti-AHNAK Nucleoprotein (AHNAK) (N-Term) antibodyAHNAK 适用: 人, 小鼠 WB, IP, IHC (fro), IF 宿主: 小鼠 Monoclonal EM-09 unconjugated
anti-AHNAK Nucleoprotein (AHNAK) (AA 1-100) antibodyAHNAK 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-AHNAK Nucleoprotein (AHNAK) (AA 1-149) antibodyAHNAK 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-AHNAK Nucleoprotein (AHNAK) (AA 1-149) antibodyAHNAK 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-AHNAK Nucleoprotein (AHNAK) (C-Term) antibodyAHNAK 适用: 人, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Immunocytochemistry: Positive control: HeLa human cervix carcinoma cell line, permeabilization is required.
Western blotting: Positive control: HeLa human cervix carcinoma cell line. - 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Do not freeze.
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: "Proteomic analysis reveals new cardiac-specific dystrophin-associated proteins." in: PLoS ONE, Vol. 7, Issue 8, pp. e43515, (2012) (PubMed).
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: "Proteomic analysis reveals new cardiac-specific dystrophin-associated proteins." in: PLoS ONE, Vol. 7, Issue 8, pp. e43515, (2012) (PubMed).
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- 抗原
- AHNAK (AHNAK Nucleoprotein (AHNAK))
- 别名
- AHNAK1 (AHNAK 产品)
- 别名
- AHNAKRS antibody, 1110004P15Rik antibody, 2310047C17Rik antibody, AA589382 antibody, AV091586 antibody, DY6 antibody, AHNAK 1 antibody, RGD1308572 antibody, UV118 antibody, AHNAK antibody, wu:fb05a01 antibody, wu:fu74f12 antibody, LOC733715 antibody, AHNAK nucleoprotein antibody, AHNAK nucleoprotein (desmoyokin) antibody, AHNAK nucleoprotein pseudogene antibody, AHNAK antibody, Ahnak antibody, ahnak antibody, LOC748622 antibody
- 背景
- AHNAK1 nucleoprotein,AHNAK1 (Desmoyokin) is a large (700 kDa) scaffold protein that translocates to the plasma membrane after an increas of extracellular calcium level or upon proteinkinase C activation and regulates extracellular calcium influx mediated by L-type Ca2+ channels. AHNAK1 has been implicated in diverse signal transduction proceses affecting cell differentiation and proliferation. In response to calcium-dependent intercellular contacts AHNAK1 forms multimeric complexes in the plasma membrane, connected with actin and annexin 2/S100A10 assemblies and is thus involved in organization of the plasma membrane architecture. In epithelial cells, AHNAK1 is localized in cytoplasm or is membrane-associated, but in cells of nonepithelial origin AHNAK1 is predominantly nuclear, it has a weak DNA-binding activity and associates with the DNA-ligase IV-XRCC4 complex.,Desmoyokin
- 基因ID
- 79026
- UniProt
- Q09666
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