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TNF alpha 抗体 (AA 1-233)

TNF alpha 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3020863
发货至: 中国
  • 抗原 See all TNF alpha 抗体
    TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
    抗原表位
    • 43
    • 32
    • 15
    • 15
    • 14
    • 13
    • 10
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-233
    适用
    • 330
    • 188
    • 122
    • 65
    • 50
    • 44
    • 30
    • 26
    • 21
    • 16
    • 11
    • 10
    • 9
    • 9
    • 6
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 271
    • 191
    • 28
    • 25
    • 6
    • 2
    • 2
    • 1
    克隆类型
    • 288
    • 231
    多克隆
    标记
    • 245
    • 79
    • 46
    • 21
    • 17
    • 12
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This TNF alpha antibody is un-conjugated
    应用范围
    • 346
    • 202
    • 127
    • 122
    • 74
    • 56
    • 56
    • 49
    • 46
    • 40
    • 39
    • 38
    • 37
    • 32
    • 20
    • 12
    • 10
    • 9
    • 9
    • 8
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    序列
    MSTESMIRDV ELAEEALPKK TGGPQGSRRC LFLSLFSFLI VAGATTLFCL LHFGVIGPQR EEFPRDLSLI SPLAQAVRSS SRTPSDKPVA HVVANPQAEG QLQWLNRRAN ALLANGVELR DNQLVVPSEG LYLIYSQVLF KGQGCPSTHV LLTHTISRIA VSYQTKVNLL SAIKSPCQRE TPEGAEAKPW YEPIYLGGVF QLEKGDRLSA EINRPDYLDF AESGQVYFGI IAL
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-233 of human TNF (NP_000585.2).
    亚型
    IgG
    Top Product
    Discover our top product TNF alpha Primary Antibody
  • 应用备注
    WB,1:1000 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze / thaw cycles
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Qin, Yang, Huang, Du, Mai, Xiao, Lü: "Sulforaphane attenuates microglia-mediated neuronal necroptosis through down-regulation of MAPK/NF-κB signaling pathways in LPS-activated BV-2 microglia." in: Pharmacological research, Vol. 133, pp. 218-235, (2018) (PubMed).

    Liu, Xia, Zhang, Jin, Zhao, Zhang, Li, Zhou, Tu, Kong, Sun, Shi, Zhao: "Micro124-mediated AHR expression regulates the inflammatory response of chronic rhinosinusitis (CRS) with nasal polyps." in: Biochemical and biophysical research communications, Vol. 500, Issue 2, pp. 145-151, (2018) (PubMed).

    Yang, Zhang, Wang, Zhang, Li: "Puerarin decreases bone loss and collagen destruction in rats with ligature-induced periodontitis." in: Journal of periodontal research, Vol. 50, Issue 6, pp. 748-57, (2017) (PubMed).

    Xu, Zhang, Lu, Deng, Zhao, Zhao, Zhao: "Prevention of Hippocampal Neuronal Damage and Cognitive Function Deficits in Vascular Dementia by Dextromethorphan." in: Molecular neurobiology, Vol. 53, Issue 5, pp. 3494-502, (2016) (PubMed).

  • 抗原
    TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
    别名
    TNF (TNF alpha 产品)
    别名
    DIF antibody, TNF-alpha antibody, TNFA antibody, TNFSF2 antibody, RATTNF antibody, Tnfa antibody, tnf antibody, TNF-a antibody, TNFalpha antibody, Tnfsf1a antibody, TNFa antibody, cTNF antibody, Tnf-alpha antibody, tnfa-like antibody, TNF-ALPHA antibody, dif antibody, tnfa antibody, xtnf antibody, tnfsf2 antibody, tnf-alpha antibody, Cachectin antibody, tumor necrosis factor antibody, tumor necrosis factor b (TNF superfamily, member 2) antibody, tumor necrosis factor alpha antibody, tumor necrosis factor a (TNF superfamily, member 2) antibody, TNF antibody, Tnf antibody, tnf antibody, tnfb antibody, tnf-alpha antibody, LOC103694380 antibody, tnfa antibody
    背景
    This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.,TNF,DIF,TNF-alpha,TNFA,TNFSF2,TNLG1F,TNF alpha,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Growth factor,TNF,Death Receptor Signaling Pathway,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Endocrine and metabolic diseases,Metabolic disorders,Immunology & Inflammation,Cytokines,TNF,NF-kB Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Cardiovascular,TNF
    分子量
    25 kDa
    基因ID
    7124
    UniProt
    P01375
    途径
    NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome
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