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- 抗原 See all IGF1R 抗体
- IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
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抗原表位
- AA 660-760
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IGF1R antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- HNYCSKDKIP IRKYADGTID IEEVTENPKT EVCGGEKGPC CACPKTEAEK QAEKEEAEYR KVFENFLHNS IFVPRPERKR RDVMQVANTT MSSRSRNTTA A
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- A synthetic peptide corresponding to a sequence within amino acids 660-760 of human IGF1R (NP_000866.1).
- 亚型
- IgG
- Top Product
- Discover our top product IGF1R Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid freeze / thaw cycles
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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miR-206 modulates lipopolysaccharide-mediated inflammatory cytokine production in human astrocytes." in: Cellular signalling, Vol. 27, Issue 1, pp. 61-8, (2015) (PubMed).
: "MiR-223 suppresses endometrial carcinoma cells proliferation by targeting IGF-1R." in: American journal of translational research, Vol. 6, Issue 6, pp. 841-9, (2015) (PubMed).
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miR-206 modulates lipopolysaccharide-mediated inflammatory cytokine production in human astrocytes." in: Cellular signalling, Vol. 27, Issue 1, pp. 61-8, (2015) (PubMed).
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- 抗原
- IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
- 别名
- IGF1R (IGF1R 产品)
- 别名
- CMT2N antibody, CD221 antibody, IGFIR antibody, IGFR antibody, JTK13 antibody, IGFIRC antibody, IGFR1 antibody, IGF-1R antibody, IGF1R antibody, DKFZp469I0618 antibody, igf-1r antibody, xIGF-1R antibody, xIGFR antibody, xigf1r antibody, A330103N21Rik antibody, D930020L01 antibody, hyft antibody, igf-ir antibody, IGF-IR antibody, IGF-IRb antibody, wu:fb03h06 antibody, IGF-IRa antibody, sb:eu1090 antibody, wu:fi20b10 antibody, alanyl-tRNA synthetase antibody, insulin like growth factor 1 receptor antibody, insulin-like growth factor 1 receptor antibody, insulin-like growth factor 1 antibody, insulin-like growth factor I receptor antibody, insulin like growth factor 1 receptor S homeolog antibody, insulin-like growth factor 1b receptor antibody, insulin-like growth factor 1a receptor antibody, AARS antibody, IGF1R antibody, Igf1r antibody, igf1r antibody, Igf1 antibody, LOC780503 antibody, LOC100136427 antibody, igf1r.S antibody, igf1rb antibody, igf1ra antibody
- 背景
- This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.,IGF1R,CD221,IGFIR,IGFR,JTK13,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Apoptosis,Growth factor,Insulin and insulin-like,ESC Pluripotency and Differentiation,Immunology & Inflammation,CD markers,Cardiovascular,Angiogenesis,IGF1R
- 分子量
- 154 kDa
- 基因ID
- 3480
- UniProt
- P08069
- 途径
- RTK signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
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