GDF15 抗体 (AA 49-308)
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- 抗原 See all GDF15 抗体
- GDF15 (Growth Differentiation Factor 15 (GDF15))
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抗原表位
- AA 49-308
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GDF15 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
- 序列
- EDSRFRELRK RYEDLLTRLR ANQSWEDSNT DLVPAPAVRI LTPEVRLGSG GHLHLRISRA ALPEGLPEAS RLHRALFRLS PTASRSWDVT RPLRRQLSLA RPQAPALHLR LSPPPSQSDQ LLAESSSARP QLELHLRPQA ARGRRRARAR NGDHCPLGPG RCCRLHTVRA SLEDLGWADW VLSPREVQVT MCIGACPSQF RAANMHAQIK TSLHRLKPDT VPAPCCVPAS YNPMVLIQKT DTGVSLQTYD DLLAKDCHCI
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 49-308 of human GDF15 (NP_004855.2).
- 亚型
- IgG
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200,IP,1:50 - 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid freeze / thaw cycles
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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Prostate cancer promotes a vicious cycle of bone metastasis progression through inducing osteocytes to secrete GDF15 that stimulates prostate cancer growth and invasion." in: Oncogene, Vol. 38, Issue 23, pp. 4540-4559, (2019) (PubMed).
: "CXXC4 activates apoptosis through up-regulating GDF15 in gastric cancer." in: Oncotarget, Vol. 8, Issue 61, pp. 103557-103567, (2017) (PubMed).
: "Growth differentiation factor-15: a p53- and demethylation-upregulating gene represses cell proliferation, invasion, and tumorigenesis in bladder carcinoma cells." in: Scientific reports, Vol. 5, pp. 12870, (2016) (PubMed).
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Prostate cancer promotes a vicious cycle of bone metastasis progression through inducing osteocytes to secrete GDF15 that stimulates prostate cancer growth and invasion." in: Oncogene, Vol. 38, Issue 23, pp. 4540-4559, (2019) (PubMed).
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- 抗原
- GDF15 (Growth Differentiation Factor 15 (GDF15))
- 别名
- GDF15 (GDF15 产品)
- 别名
- GDF15 antibody, GDF-15 antibody, MIC-1 antibody, MIC1 antibody, NAG-1 antibody, PDF antibody, PLAB antibody, PTGFB antibody, SBF antibody, growth differentiation factor 15 antibody, GDF15 antibody, Gdf15 antibody
- 背景
- The protein encoded by this gene belongs to the transforming growth factor-beta (TGF-beta) family. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress reponse program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress.,GDF15,GDF-15,MIC-1,MIC1,NAG-1,PDF,PLAB,PTGFB,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cytoskeleton,Extracellular Matrix,Bone,Growth factor,Immunology & Inflammation,Cytokines,Cardiovascular,Heart,Hypertrophy,GDF15
- 分子量
- 34 kDa
- 基因ID
- 9518
- UniProt
- Q99988
- 途径
- SARS-CoV-2 Protein Interactome
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