CG9648 antibody, Dmel\\CG9648 antibody, MAX antibody, bHLHd9 antibody, dMax antibody, dmax antibody, max antibody, bhlhd4 antibody, bhlhd5 antibody, bhlhd6 antibody, bhlhd7 antibody, bhlhd8 antibody, xmax2 antibody, xmax4 antibody, xmax antibody, AA960152 antibody, AI875693 antibody, bHLHd4 antibody, bHLHd5 antibody, bHLHd6 antibody, bHLHd7 antibody, bHLHd8 antibody, fa92b04 antibody, fb52a04 antibody, fb95h11 antibody, wu:fa92b04 antibody, wu:fb52a04 antibody, wu:fb95h11 antibody, zmax antibody, CG9648 gene product from transcript CG9648-RD antibody, MYC associated factor X L homeolog antibody, MYC associated factor X antibody, Max protein antibody, MYC associated factor X S homeolog antibody, myc associated factor X antibody, Max antibody, max.L antibody, MAX antibody, max antibody, max.S antibody
背景
The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants.,MAX,bHLHd4,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Tumor suppressors,Signal Transduction,MAPK-P38 Signaling Pathway,Protein phosphorylation,MAX