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- 抗原 See all MEK1 (MAP2K1) 抗体
- MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
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抗原表位
- pSer298
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MEK1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 序列
- PLSSY
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Phosphorylated Antibodies
- 免疫原
- A synthetic phosphorylated peptide around S298 of human MEK1 (NP_002746.1).
- 亚型
- IgG
- Top Product
- Discover our top product MAP2K1 Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000,IP,1:50 - 1:100
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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MCM6 promotes metastasis of hepatocellular carcinoma via MEK/ERK pathway and serves as a novel serum biomarker for early recurrence." in: Journal of experimental & clinical cancer research : CR, Vol. 37, Issue 1, pp. 10, (2018) (PubMed).
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MCM6 promotes metastasis of hepatocellular carcinoma via MEK/ERK pathway and serves as a novel serum biomarker for early recurrence." in: Journal of experimental & clinical cancer research : CR, Vol. 37, Issue 1, pp. 10, (2018) (PubMed).
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- 抗原
- MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
- 别名
- MAP2K1 (MAP2K1 产品)
- 背景
- The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.,CFC3,MAPKK1,MEK1,MKK1,PRKMK1,MAP2K1,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Kinase,Tyrosine kinases,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cytoskeleton,Actins,ESC Pluripotency and Differentiation,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Warburg Effect,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,IL-6 Receptor Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Angiogenesis,Protein phosphorylation,MAP2K1
- 分子量
- 40 kDa/43 kDa
- 基因ID
- 5604
- UniProt
- Q02750
- 途径
- MAPK Pathway, RTK signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
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