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- 抗原 See all RAD50 抗体
- RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))
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抗原表位
- AA 1-100
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RAD50 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
- 序列
- MSRIEKMSIL GVRSFGIEDK DKQIITFFSP LTILVGPNGA GKTTIIECLK YICTGDFPPG TKGNTFVHDP KVAQETDVRA QIRLQFRDVN GELIAVQRSM
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 免疫原
- A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Rad50 (NP_005723.2).
- 亚型
- IgG
- Top Product
- Discover our top product RAD50 Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:20 - 1:50
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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The transcription factor GATA3 is required for homologous recombination repair by regulating CtIP expression." in: Oncogene, Vol. 36, Issue 36, pp. 5168-5176, (2017) (PubMed).
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The transcription factor GATA3 is required for homologous recombination repair by regulating CtIP expression." in: Oncogene, Vol. 36, Issue 36, pp. 5168-5176, (2017) (PubMed).
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- 抗原
- RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))
- 别名
- RAD50 (RAD50 产品)
- 别名
- NBSLD antibody, RAD502 antibody, hRad50 antibody, Mrell antibody, Rad50l antibody, 6339 antibody, CG6339 antibody, Dmel\\CG6339 antibody, Dmrad50 antibody, RAD50 antibody, Rad50 antibody, ATRAD50 antibody, DNA REPAIR-RECOMBINATION PROTEIN antibody, F22D22.28 antibody, F22D22_28 antibody, SPAP4C9.01c antibody, im:6906849 antibody, si:ch211-79h18.3 antibody, RAD50 double strand break repair protein antibody, CG6339 gene product from transcript CG6339-RE antibody, RAD50 homolog, double strand break repair protein L homeolog antibody, rad50 antibody, DNA repair protein RAD50 antibody, RAD50 homolog, double strand break repair protein antibody, DNA repair-recombination protein (RAD50) antibody, MRX complex DNA-binding subunit antibody, DNA repair protein Rad50 antibody, RAD50 recombination protein antibody, Rad50 DNA repair/recombination protein antibody, DNA repair protein rad-50 antibody, RAD50 antibody, Rad50 antibody, rad50 antibody, rad50.L antibody, LOC658288 antibody, LOC726642 antibody, rad-50 antibody
- 背景
- The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.,RAD50,NBSLD,RAD502,hRad50,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cell Biology & Developmental Biology,Cell Cycle,G2/M DNA Damage Checkpoint,RAD50
- 分子量
- 138 kDa/153 kDa/154 kDa
- 基因ID
- 10111
- UniProt
- Q92878
- 途径
- DNA Damage Repair, Protein targeting to Nucleus
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