NFASC 抗体 (AA 830-1100)
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北京 101111
Quick Overview for NFASC 抗体 (AA 830-1100) (ABIN3017267)
抗原
See all NFASC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 830-1100
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序列
- RFRVRQPNLE TINLEWDHPE HPNGIMIGYT LKYVAFNGTK VGKQIVENFS PNQTKFTVQR TDPVSRYRFT LSARTQVGSG EAVTEESPAP PNEATPTAAP PTLPPTTVGA TGAVSSTDAT AIAATTEATT VPIIPTVAPT TIATTTTVAT TTTTTAAATT TTESPPTTTS GTKIHESAPD EQSIWNVTVL PNSKWANITW KHNFGPGTDF VVEYIDSNHT KKTVPVKAQA QPIQLTDLYP GMTYTLRVYS RDNEGISSTV ITFMTSTAYT N
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 830-1100 of human NFASC (NP_001005388.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- NFASC (Neurofascin (NFASC))
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别名
- NFASC
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背景
- This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined.,NFASC,NF,NRCAML,Neuroscience,NFASC
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分子量
- 69 kDa/119 kDa/130-150 kDa
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基因ID
- 23114
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UniProt
- O94856
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途径
- Cell-Cell Junction Organization
抗原
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