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CCR2 抗体 (AA 315-374)

CCR2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3016845
发货至: 中国
  • 抗原 See all CCR2 抗体
    CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
    抗原表位
    • 16
    • 9
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 315-374
    适用
    • 92
    • 47
    • 40
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 82
    • 9
    • 4
    • 1
    克隆类型
    • 77
    • 18
    • 1
    多克隆
    标记
    • 40
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CCR2 antibody is un-conjugated
    应用范围
    • 38
    • 24
    • 23
    • 15
    • 13
    • 12
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    序列
    LFHIALGCRI APLQKPVCGG PGVRPGKNVK VTTQGLLDGR GKGKSIGRAP EASLQDKEGA
    交叉反应
    人, 小鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 315-374 of human CCR2 (NP_001116513.2).
    亚型
    IgG
    Top Product
    Discover our top product CCR2 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Deci, Ferguson, Scatigno, Nguyen: "Modulating Macrophage Polarization through CCR2 Inhibition and Multivalent Engagement." in: Molecular pharmaceutics, Vol. 15, Issue 7, pp. 2721-2731, (2018) (PubMed).

  • 抗原
    CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
    别名
    CCR2 (CCR2 产品)
    别名
    CC-CKR-2 antibody, CCR-2 antibody, CCR2A antibody, CCR2B antibody, CD192 antibody, CKR2 antibody, CKR2A antibody, CKR2B antibody, CMKBR2 antibody, MCP-1-R antibody, ACKR5 antibody, CKRX antibody, CRAM antibody, CRAM-A antibody, CRAM-B antibody, HCR antibody, Cc-ckr-2 antibody, Ccr2a antibody, Ccr2b antibody, Ckr2 antibody, Ckr2a antibody, Ckr2b antibody, Cmkbr2 antibody, mJe-r antibody, C-C motif chemokine receptor 2 antibody, C-C motif chemokine receptor like 2 antibody, chemokine (C-C motif) receptor 2 antibody, CCR2 antibody, CCRL2 antibody, Ccr2 antibody, LOC484790 antibody
    背景
    This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.,CCR2,CC-CKR-2,CCR-2,CCR2A,CCR2B,CD192,CKR2,CKR2A,CKR2B,CMKBR2,MCP-1-R,FLJ78302,Cancer,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Immunology & Inflammation,CD markers,Cell Intrinsic Innate Immunity Signaling Pathway,Chemokines,Chemokine,Cardiovascular,CCR2
    分子量
    41 kDa
    基因ID
    729230
    UniProt
    P41597
    途径
    cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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